Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ID09_RS09365 Genome accession   NZ_CP008921
Coordinates   1911793..1912515 (-) Length   240 a.a.
NCBI ID   WP_024381052.1    Uniprot ID   A0A075SG27
Organism   Streptococcus suis 6407     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1906793..1917515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS09345 (ID09_09590) - 1906885..1908111 (-) 1227 WP_029693747.1 cysteine desulfurase -
  ID09_RS09350 (ID09_09595) sufD 1908113..1909375 (-) 1263 WP_024381049.1 Fe-S cluster assembly protein SufD -
  ID09_RS09355 (ID09_09600) sufC 1909392..1910165 (-) 774 WP_024381050.1 Fe-S cluster assembly ATPase SufC -
  ID09_RS09360 (ID09_09605) - 1910624..1911796 (-) 1173 WP_024381051.1 glycosyltransferase family 4 protein -
  ID09_RS09365 (ID09_09610) mecA 1911793..1912515 (-) 723 WP_024381052.1 adaptor protein MecA Regulator
  ID09_RS09370 (ID09_09615) - 1912643..1913479 (-) 837 WP_015647359.1 undecaprenyl-diphosphate phosphatase -
  ID09_RS09375 (ID09_09620) - 1913606..1915171 (+) 1566 WP_029693748.1 ABC transporter substrate-binding protein/permease -
  ID09_RS09380 (ID09_09625) - 1915164..1915907 (+) 744 WP_024381054.1 amino acid ABC transporter ATP-binding protein -
  ID09_RS09385 (ID09_09630) - 1916033..1916242 (-) 210 WP_009910800.1 hypothetical protein -
  ID09_RS09390 (ID09_09635) - 1916328..1917230 (-) 903 WP_002937414.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28001.52 Da        Isoelectric Point: 4.0497

>NTDB_id=125714 ID09_RS09365 WP_024381052.1 1911793..1912515(-) (mecA) [Streptococcus suis 6407]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTRLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=125714 ID09_RS09365 WP_024381052.1 1911793..1912515(-) (mecA) [Streptococcus suis 6407]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGCCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACTAGGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SG27

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment