Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ID09_RS05755 Genome accession   NZ_CP008921
Coordinates   1188569..1189948 (-) Length   459 a.a.
NCBI ID   WP_024381361.1    Uniprot ID   A0A075SID2
Organism   Streptococcus suis 6407     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1183569..1194948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS05735 (ID09_05900) - 1184827..1185417 (-) 591 WP_009909951.1 class I SAM-dependent methyltransferase -
  ID09_RS05740 (ID09_05905) coaA 1185527..1186447 (+) 921 WP_024381359.1 type I pantothenate kinase -
  ID09_RS05745 (ID09_05910) rpsT 1186506..1186754 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  ID09_RS05750 (ID09_05920) - 1187016..1188245 (-) 1230 WP_024381360.1 transglutaminase domain-containing protein -
  ID09_RS05755 (ID09_05925) ciaH 1188569..1189948 (-) 1380 WP_024381361.1 sensor histidine kinase Regulator
  ID09_RS05760 (ID09_05930) ciaR 1189941..1190612 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  ID09_RS12400 - 1190806..1190961 (-) 156 WP_228380904.1 hypothetical protein -
  ID09_RS12550 - 1191019..1191153 (-) 135 WP_255304292.1 hypothetical protein -
  ID09_RS05770 (ID09_05940) phoU 1191319..1191975 (-) 657 WP_024390542.1 phosphate signaling complex protein PhoU -
  ID09_RS05775 (ID09_05945) pstB 1192004..1192762 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  ID09_RS05780 (ID09_05950) pstB 1192774..1193577 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  ID09_RS05785 (ID09_05955) pstA 1193602..1194489 (-) 888 WP_024381362.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51961.70 Da        Isoelectric Point: 6.8882

>NTDB_id=125700 ID09_RS05755 WP_024381361.1 1188569..1189948(-) (ciaH) [Streptococcus suis 6407]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=125700 ID09_RS05755 WP_024381361.1 1188569..1189948(-) (ciaH) [Streptococcus suis 6407]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SID2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae D39

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae R6

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.345

99.782

0.492
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488

Multiple sequence alignment