Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ID09_RS05350 Genome accession   NZ_CP008921
Coordinates   1104709..1106859 (-) Length   716 a.a.
NCBI ID   WP_024390738.1    Uniprot ID   A0A075SR29
Organism   Streptococcus suis 6407     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1099709..1111859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS05330 (ID09_05490) - 1101217..1101852 (-) 636 WP_024381040.1 hypothetical protein -
  ID09_RS05335 (ID09_05495) - 1102439..1103188 (-) 750 WP_024381039.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  ID09_RS05340 (ID09_05500) - 1103203..1104072 (-) 870 WP_228380944.1 GHKL domain-containing protein -
  ID09_RS05345 (ID09_05505) - 1104532..1104687 (-) 156 WP_024381037.1 hypothetical protein -
  ID09_RS05350 (ID09_05510) comA 1104709..1106859 (-) 2151 WP_024390738.1 peptide cleavage/export ABC transporter Regulator
  ID09_RS05355 (ID09_05515) - 1107063..1107254 (-) 192 WP_024381035.1 hypothetical protein -
  ID09_RS05360 (ID09_05520) - 1107343..1107615 (-) 273 WP_024381592.1 DUF3884 family protein -
  ID09_RS05365 (ID09_05525) - 1107644..1108960 (-) 1317 WP_024381593.1 glycosyltransferase family 2 protein -
  ID09_RS05370 (ID09_05530) - 1109103..1109309 (-) 207 Protein_1027 putative cross-wall-targeting lipoprotein signal domain-containing proteiin -
  ID09_RS05375 (ID09_05535) - 1109551..1110144 (-) 594 WP_024381595.1 PBECR4 domain-containing protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81593.42 Da        Isoelectric Point: 6.6053

>NTDB_id=125699 ID09_RS05350 WP_024390738.1 1104709..1106859(-) (comA) [Streptococcus suis 6407]
MKFSKRHYRAQVDSKDCGVAALAMVLEYYNSHYSLAELREMLGTTENGTTAFSIVSVANELGFDTEAIYADISLFDIEDI
KFPFIVHINKNNKFYHYYVIIGSDKKYIYIADPDPLIKLSKLTKEQFLAEWRGITILLKPNHEYKIKIKKTSFPSLFTLL
FNQKKLIFLIILLTLAVNFINIIGSYYLKRVIDSYIPKGELDFLNLMSISLIVIYLMQQFFVFGQGVLITVLSQILSKNI
MLSYIAHLFKLPLSFFATRRTGDIVSRFSDANIIIEVLSSIILSVILDVSIVTGVSIVLFLQSSYLFFIIIIAFPIYALV
IFLFMKPFRRSKTSVMEAGASLSSVLIEDINGIETIKSLTSEVDRYKKIKDEFSNYYKKITFYSRMELFQDVLKNFTQLL
FNVLILWQGAILVIEGKISLGSLITFNTLELYFLNSLENIINLQPKFQSASVAYNRLEEIYSVQSEFQDKFFITNFKLNS
SKIVISNLTYKYGYNQPLLKDINLVIEEGCKIAFVGLSGSGKTTLAKMLVNFMPPTYGSIEFGGININDIDKKTLRQLIN
YIPQKPYIFNGTILDNLLLGVEDEISFEEINKATEIAEIKSVIENLPLGYETELSTEHSILSGGQLQRVAIARALLTNPS
VLILDESTSNLDNLTERKIIDNLMSLDITVIFIAHRLNITEQVERIFVIENGMIIENGNHEDLILKQGFYSKILKG

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=125699 ID09_RS05350 WP_024390738.1 1104709..1106859(-) (comA) [Streptococcus suis 6407]
ATGAAATTTTCGAAACGTCATTATCGTGCTCAAGTTGATTCAAAAGATTGTGGAGTAGCTGCTTTGGCCATGGTGTTAGA
ATACTATAATTCACATTATTCTTTAGCAGAACTTAGAGAAATGTTAGGTACAACTGAAAATGGGACTACTGCATTTAGTA
TAGTTTCTGTGGCAAATGAATTAGGGTTCGATACTGAAGCTATTTATGCAGATATTTCTTTATTTGACATAGAGGATATA
AAATTTCCATTTATTGTACATATAAATAAGAATAATAAATTTTATCATTACTATGTTATTATTGGCAGTGATAAAAAATA
TATTTATATAGCTGATCCTGATCCTCTGATAAAATTATCTAAACTAACTAAAGAACAGTTTCTTGCAGAATGGAGAGGGA
TAACAATATTATTAAAACCAAACCATGAGTACAAAATTAAAATAAAGAAGACAAGTTTTCCTTCTTTATTTACTTTACTG
TTTAATCAAAAGAAATTAATTTTTTTAATTATATTATTAACTTTAGCAGTAAACTTTATAAATATAATTGGTTCATACTA
TTTAAAGAGAGTAATTGATTCTTATATTCCTAAAGGGGAGCTGGATTTTCTTAATCTAATGTCAATAAGCCTAATTGTTA
TTTATCTTATGCAACAGTTTTTTGTATTTGGTCAAGGGGTATTGATAACAGTTCTAAGTCAAATACTTTCAAAAAATATA
ATGCTGTCATATATTGCTCACCTTTTTAAACTGCCTCTATCTTTTTTTGCAACAAGAAGAACTGGCGATATTGTCTCTAG
ATTTTCAGATGCTAATATCATAATTGAAGTATTATCTAGTATAATTTTATCTGTAATACTAGATGTGTCAATAGTTACTG
GAGTATCAATTGTACTTTTTTTGCAAAGTAGTTATTTATTTTTTATTATAATTATTGCGTTTCCAATTTATGCTTTAGTA
ATTTTTTTATTCATGAAACCATTTAGACGTAGTAAAACTAGTGTAATGGAAGCAGGAGCTTCACTTTCCTCAGTTCTTAT
AGAAGATATAAATGGAATAGAGACAATAAAATCTCTTACTAGTGAGGTAGATCGCTATAAAAAAATAAAAGACGAATTTA
GTAATTATTATAAAAAAATTACTTTTTATAGTAGAATGGAGTTGTTTCAAGATGTGTTAAAAAATTTTACTCAATTGTTG
TTTAATGTATTAATTTTATGGCAAGGTGCTATTTTAGTAATTGAAGGAAAAATATCATTGGGATCTTTGATAACCTTTAA
TACTTTAGAACTTTATTTTCTGAATTCACTGGAGAACATTATTAATTTACAACCTAAATTTCAATCAGCAAGTGTTGCGT
ATAATAGATTAGAAGAAATCTATTCGGTTCAATCGGAATTTCAGGATAAGTTCTTCATAACAAATTTTAAATTGAATTCT
AGTAAGATAGTAATTTCAAATTTAACCTACAAATATGGCTATAACCAGCCTCTATTAAAAGATATTAATTTAGTTATCGA
GGAAGGTTGTAAAATAGCATTTGTTGGTCTTTCTGGTTCAGGGAAAACAACTCTAGCAAAAATGTTAGTTAATTTTATGC
CTCCTACCTATGGAAGTATTGAATTTGGAGGAATTAATATTAATGATATTGATAAGAAGACTTTGAGACAATTGATTAAT
TATATACCTCAGAAACCTTATATTTTTAACGGTACTATATTAGATAATCTTTTATTAGGTGTTGAAGATGAAATTTCATT
TGAAGAGATTAATAAAGCTACTGAGATTGCCGAGATAAAATCTGTTATAGAGAATTTACCGTTAGGATATGAGACCGAAC
TTTCCACTGAACATAGCATTTTGTCAGGAGGTCAACTTCAGAGAGTTGCTATTGCACGTGCATTATTAACCAATCCTTCG
GTATTAATCTTAGATGAGTCAACAAGTAATTTGGATAATTTAACGGAAAGAAAAATTATTGATAATTTAATGAGCTTGGA
TATAACTGTAATATTTATTGCTCACCGTCTTAATATAACAGAACAGGTTGAAAGGATATTTGTCATAGAAAATGGTATGA
TAATCGAAAACGGAAATCATGAAGATTTGATATTAAAACAAGGGTTTTATTCTAAAATATTAAAAGGTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-649)

ABC transporter transmembrane region (ABC_membrane)

(167-437)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SR29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.224

99.86

0.561
  comA Streptococcus gordonii str. Challis substr. CH1

56.224

99.86

0.561
  comA Streptococcus mitis SK321

55.664

99.86

0.556
  comA Streptococcus pneumoniae R6

55.385

99.86

0.553
  comA Streptococcus pneumoniae Rx1

55.385

99.86

0.553
  comA Streptococcus pneumoniae D39

55.385

99.86

0.553
  comA Streptococcus pneumoniae TIGR4

55.105

99.86

0.55
  comA/nlmT Streptococcus mutans UA159

49.157

99.441

0.489

Multiple sequence alignment