Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   TK78_RS30180 Genome accession   NZ_CP010833
Coordinates   6823420..6824040 (-) Length   206 a.a.
NCBI ID   WP_075267302.1    Uniprot ID   -
Organism   Streptomyces sp. Tue 6075 strain Tue6075     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6818420..6829040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TK78_RS30160 (TK78_29630) - 6818996..6820225 (-) 1230 WP_075267299.1 DUF349 domain-containing protein -
  TK78_RS30165 (TK78_29635) - 6820440..6821228 (-) 789 WP_075267300.1 peptidylprolyl isomerase -
  TK78_RS30170 (TK78_29640) - 6821386..6822075 (+) 690 WP_030712572.1 MBL fold metallo-hydrolase -
  TK78_RS30175 (TK78_29645) hisS 6822093..6823355 (+) 1263 WP_075267301.1 histidine--tRNA ligase -
  TK78_RS30180 (TK78_29650) vraR 6823420..6824040 (-) 621 WP_075267302.1 response regulator transcription factor Regulator
  TK78_RS30185 (TK78_29655) - 6824040..6825302 (-) 1263 WP_075267303.1 sensor histidine kinase -
  TK78_RS30190 (TK78_29660) - 6825260..6826081 (-) 822 WP_075267304.1 ABC transporter permease -
  TK78_RS30195 (TK78_29665) - 6826078..6826935 (-) 858 WP_107472836.1 ABC transporter ATP-binding protein -
  TK78_RS30200 (TK78_29670) - 6827072..6827710 (+) 639 WP_006123204.1 vitamin K epoxide reductase family protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21942.41 Da        Isoelectric Point: 5.7852

>NTDB_id=124768 TK78_RS30180 WP_075267302.1 6823420..6824040(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
MIRVLLADDHPVVREGLRGMLDAEADLDVVGEADSGPRAEALCAELLPDIVLMDLRMPGGGGVESIRRIRAAGLSCRVVV
LTTYESDGDILRAVEAGASGYLLKDLGRGELADAIRAAARGETVLAPTVATRLVDRLRGVPELPRLSERETQVLRLVAEG
CTNAEIGRKLFIGESTVKTHLLRIFGKLGVSDRTAAVTGAMRHGLL

Nucleotide


Download         Length: 621 bp        

>NTDB_id=124768 TK78_RS30180 WP_075267302.1 6823420..6824040(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
ATGATCCGTGTCCTGCTGGCCGACGACCACCCCGTCGTACGGGAGGGGCTGCGCGGGATGCTGGACGCCGAGGCGGACCT
CGACGTGGTCGGCGAGGCCGACAGCGGTCCCCGTGCCGAGGCCCTGTGCGCCGAACTGCTGCCGGACATCGTGCTGATGG
ATCTGCGGATGCCGGGCGGCGGGGGCGTCGAGTCGATCCGCCGGATACGAGCGGCGGGGCTGTCCTGCCGGGTCGTGGTG
CTGACCACGTACGAGAGCGACGGCGACATCCTGCGGGCGGTGGAGGCCGGGGCGTCCGGCTATCTGCTCAAGGACCTGGG
CCGGGGCGAGCTGGCGGACGCGATCCGGGCCGCGGCGCGGGGCGAGACGGTGCTCGCGCCGACGGTGGCGACCCGGCTGG
TGGACCGGCTGCGCGGGGTGCCGGAGCTGCCGCGGCTCTCGGAGCGGGAGACGCAGGTGCTGCGGCTGGTGGCGGAGGGG
TGCACCAACGCGGAGATCGGGCGGAAGCTGTTCATCGGGGAGTCGACGGTGAAGACCCATCTGCTGCGGATCTTCGGCAA
GCTGGGCGTCAGCGACCGTACGGCGGCGGTGACGGGGGCGATGCGCCACGGGCTGCTGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.262

100

0.413
  degU Bacillus subtilis subsp. subtilis str. 168

34.978

100

0.379
  letA Legionella pneumophila str. Paris

36.842

100

0.374
  letA Legionella pneumophila strain ERS1305867

36.842

100

0.374

Multiple sequence alignment