Detailed information NTG0124465

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DR75_RS09555
• Genome accession: NZ_CP008816
• Coordinates: 1795542..1796840 (+)
• Length: 432 a.a.
• NCBI ID: WP_002415025.1
• Uniprot ID: -
• Organism: Enterococcus faecalis ATCC 29212
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1790542..1801840

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DR75_RS09550 (DR75_1759)	rlmH	1794662..1795141 (-)	480	WP_002355021.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DR75_RS09555 (DR75_1760)	htrA	1795542..1796840 (+)	1299	WP_002415025.1	S1C family serine protease	Regulator
DR75_RS09560 (DR75_1761)	ytpR	1796887..1797507 (-)	621	WP_002355018.1	YtpR family tRNA-binding protein	-
DR75_RS09565 (DR75_1762)	-	1797718..1798173 (-)	456	WP_002385249.1	universal stress protein	-
DR75_RS09570 (DR75_1763)	-	1798321..1798635 (-)	315	WP_002355015.1	thioredoxin family protein	-
DR75_RS09575 (DR75_1764)	pepA	1798647..1799723 (-)	1077	WP_002355013.1	glutamyl aminopeptidase	-
DR75_RS09580 (DR75_1765)	-	1800030..1800371 (+)	342	WP_002404031.1	PepSY domain-containing protein	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 44845.98 Da
• Isoelectric Point: 4.9968

>NTDB_id=124465 DR75_RS09555 WP_002415025.1 1795542..1796840(+) (htrA) [Enterococcus faecalis ATCC 29212]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSIINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide

• Length: 1299 bp

>NTDB_id=124465 DR75_RS09555 WP_002415025.1 1795542..1796840(+) (htrA) [Enterococcus faecalis ATCC 29212]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCTCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTATCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCGATTG
GTTCCCCTCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCCGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGCGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (319-416)

• Peptidase family M50 (Peptidase_M50) (9-416)

• Trypsin-like peptidase domain (Trypsin_2) (132-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	52.927	94.907	0.502
htrA	Streptococcus mutans UA159	58.356	84.491	0.493
htrA	Streptococcus mitis NCTC 12261	54.865	85.648	0.47
htrA	Streptococcus pneumoniae TIGR4	55.524	81.713	0.454
htrA	Streptococcus pneumoniae Rx1	55.524	81.713	0.454
htrA	Streptococcus pneumoniae D39	55.524	81.713	0.454
htrA	Streptococcus pneumoniae R6	55.524	81.713	0.454