Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   C645_RS03035 Genome accession   NZ_CP008740
Coordinates   583118..583624 (-) Length   168 a.a.
NCBI ID   WP_005656467.1    Uniprot ID   -
Organism   Haemophilus influenzae 2019     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 578118..588624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C645_RS03005 (C645_03060) nudC 578611..579405 (-) 795 WP_005656457.1 NAD(+) diphosphatase -
  C645_RS03010 (C645_03065) nfuA 579472..580068 (-) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -
  C645_RS03015 (C645_03070) - 580144..580830 (-) 687 WP_005688731.1 ComF family protein -
  C645_RS03020 (C645_03075) comE 580843..582180 (-) 1338 WP_005659796.1 type IV pilus secretin PilQ family protein Machinery gene
  C645_RS03025 (C645_03080) comD 582190..582603 (-) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  C645_RS03030 (C645_03085) comC 582600..583121 (-) 522 WP_046067623.1 competence protein ComC Machinery gene
  C645_RS03035 (C645_03090) comB 583118..583624 (-) 507 WP_005656467.1 competence protein ComB Machinery gene
  C645_RS03040 (C645_03095) comA 583625..584422 (-) 798 WP_005656469.1 pilus assembly protein PilM Machinery gene
  C645_RS03045 (C645_03100) - 584518..587112 (+) 2595 WP_005656471.1 penicillin-binding protein 1A -
  C645_RS03050 (C645_03105) - 587185..588030 (+) 846 WP_005656472.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  C645_RS03055 (C645_03110) - 588183..588512 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19752.67 Da        Isoelectric Point: 9.4939

>NTDB_id=123957 C645_RS03035 WP_005656467.1 583118..583624(-) (comB) [Haemophilus influenzae 2019]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMRIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=123957 C645_RS03035 WP_005656467.1 583118..583624(-) (comB) [Haemophilus influenzae 2019]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCGAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

98.81

100

0.988
  comB Haemophilus influenzae Rd KW20

98.81

100

0.988

Multiple sequence alignment