Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   C645_RS03040 Genome accession   NZ_CP008740
Coordinates   583625..584422 (-) Length   265 a.a.
NCBI ID   WP_005656469.1    Uniprot ID   A0A0H3PE38
Organism   Haemophilus influenzae 2019     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 578625..589422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C645_RS03010 (C645_03065) nfuA 579472..580068 (-) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -
  C645_RS03015 (C645_03070) - 580144..580830 (-) 687 WP_005688731.1 ComF family protein -
  C645_RS03020 (C645_03075) comE 580843..582180 (-) 1338 WP_005659796.1 type IV pilus secretin PilQ family protein Machinery gene
  C645_RS03025 (C645_03080) comD 582190..582603 (-) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  C645_RS03030 (C645_03085) comC 582600..583121 (-) 522 WP_046067623.1 competence protein ComC Machinery gene
  C645_RS03035 (C645_03090) comB 583118..583624 (-) 507 WP_005656467.1 competence protein ComB Machinery gene
  C645_RS03040 (C645_03095) comA 583625..584422 (-) 798 WP_005656469.1 pilus assembly protein PilM Machinery gene
  C645_RS03045 (C645_03100) - 584518..587112 (+) 2595 WP_005656471.1 penicillin-binding protein 1A -
  C645_RS03050 (C645_03105) - 587185..588030 (+) 846 WP_005656472.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  C645_RS03055 (C645_03110) - 588183..588512 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  C645_RS03060 (C645_03115) recR 588642..589244 (+) 603 WP_005656473.1 recombination mediator RecR -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31589.94 Da        Isoelectric Point: 6.2348

>NTDB_id=123958 C645_RS03040 WP_005656469.1 583625..584422(-) (comA) [Haemophilus influenzae 2019]
MQFSLKNYRTLQIGIHRKQSYFDFVWFDDLEQPQSYQIFVNDRYFKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVL
MLPQVLNAQECHQQCKFVIEKELPIFLEELWFDYRSTPLKQGFRLEVTAIRKSTAQTYLQDFQPFKINVLDVASNAVLRA
FQYLLNEQARSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQFEQVFVYQIPSSHTPLPENWQRV
ETELPFIALGNVLWQKDLHQQKVGG

Nucleotide


Download         Length: 798 bp        

>NTDB_id=123958 C645_RS03040 WP_005656469.1 583625..584422(-) (comA) [Haemophilus influenzae 2019]
ATGCAATTCTCCCTGAAAAATTACCGCACTTTACAAATCGGCATTCATCGTAAGCAGAGTTATTTTGATTTTGTGTGGTT
TGATGATCTTGAACAGCCACAAAGTTATCAAATCTTTGTTAATGATCGTTATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTGCAGTTTGTAGCAAGCATTCCCGCCCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCACAAGAATGTCATCAACAATGTAAATTTGTGATTGAAAAAGAGCTGCCTATTTTTTT
AGAAGAATTGTGGTTTGATTATCGTTCTACCCCGTTAAAGCAAGGTTTTCGATTAGAGGTTACTGCAATTCGTAAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCGTCAAATGCTGTTTTGCGTGCA
TTTCAATATCTGTTGAATGAACAAGCGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGCTTGGCGAT
TTGTGAAAGATCTCAGCAATCACAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGACAATTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACGCCATTACCAGAAAACTGGCAGAGAGTA
GAAACAGAACTCCCTTTTATTGCGCTTGGCAACGTGCTATGGCAAAAAGATTTACATCAACAAAAAGTGGGTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3PE38

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

97.736

100

0.977
  comA Haemophilus influenzae 86-028NP

96.226

100

0.962

Multiple sequence alignment