Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   RU53_RS03700 Genome accession   NZ_CP010526
Coordinates   750134..750808 (+) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 745134..755808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RU53_RS03670 (RU53_716) - 745349..746416 (+) 1068 WP_000980137.1 membrane protein -
  RU53_RS03675 (RU53_717) - 746567..747610 (+) 1044 WP_001837532.1 alpha/beta hydrolase -
  RU53_RS03685 (RU53_718) - 747939..748367 (+) 429 WP_000198504.1 hypothetical protein -
  RU53_RS03690 (RU53_719) - 748576..749082 (-) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  RU53_RS03695 (RU53_720) graX 749195..750118 (+) 924 WP_000802956.1 auxiliary protein GraX/ApsX -
  RU53_RS03700 (RU53_721) braR 750134..750808 (+) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  RU53_RS03705 (RU53_722) graS 750801..751841 (+) 1041 WP_001061264.1 histidine kinase GraS/ApsS -
  RU53_RS03710 (RU53_723) vraF 751985..752746 (+) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  RU53_RS03715 (RU53_724) vraG 752736..754625 (+) 1890 WP_000143622.1 ABC transporter permease VraG -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=123958 RU53_RS03700 WP_001166500.1 750134..750808(+) (braR) [Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=123958 RU53_RS03700 WP_001166500.1 750134..750808(+) (braR) [Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCGTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATAAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397

Multiple sequence alignment