Detailed information NTG0123593

Bioinformatically predicted

Overview

• Name: amiD
• Type: Regulator
• Locus tag: FE90_RS06375
• Genome accession: NZ_CP008695
• Coordinates: 1238342..1239268 (-)
• Length: 308 a.a.
• NCBI ID: WP_002986004.1
• Uniprot ID: Q1JNF8
• Organism: Streptococcus pyogenes strain M23ND
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1233342..1244268

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FE90_RS09800 (FE90_1262)	-	1234740..1235033 (+)	294	WP_038433283.1	transposase	-
FE90_RS10140	-	1235177..1235287 (+)	111	WP_238578131.1	IS3 family transposase	-
FE90_RS10145	-	1235265..1235597 (-)	333	Protein_1237	DDE-type integrase/transposase/recombinase	-
FE90_RS10150	-	1235639..1235722 (+)	84	Protein_1238	integrase core domain-containing protein	-
FE90_RS10045 (FE90_1265)	-	1235960..1236199 (+)	240	WP_038433587.1	hypothetical protein	-
FE90_RS10355	-	1236226..1236309 (+)	84	Protein_1240	IS3 family transposase	-
FE90_RS06365 (FE90_1266)	amiF	1236347..1237270 (-)	924	WP_038433588.1	ATP-binding cassette domain-containing protein	Regulator
FE90_RS06370 (FE90_1267)	amiE	1237263..1238333 (-)	1071	WP_010921893.1	ABC transporter ATP-binding protein	Regulator
FE90_RS06375 (FE90_1268)	amiD	1238342..1239268 (-)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
FE90_RS06380 (FE90_1269)	amiC	1239268..1240770 (-)	1503	WP_011017334.1	ABC transporter permease	Regulator
FE90_RS06385 (FE90_1270)	amiA	1240835..1242805 (-)	1971	WP_038433589.1	peptide ABC transporter substrate-binding protein	Regulator
FE90_RS06390 (FE90_1271)	-	1243039..1244022 (+)	984	WP_038433590.1	IS30-like element IS1239 family transposase	-

Sequence

Protein

• Length: 308 a.a.
• Molecular weight: 34862.81 Da
• Isoelectric Point: 8.5670

>NTDB_id=123593 FE90_RS06375 WP_002986004.1 1238342..1239268(-) (amiD) [Streptococcus pyogenes strain M23ND]
MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTVFMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKR
YIWPNAEYWFGTDKNGQSLFDGVWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKNLLPQLVSVIMTMLSQMLPVYVS
SEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYLFWIPLVTLILVSLPLYIVGQNLADASDPRSHR

Nucleotide

• Length: 927 bp

>NTDB_id=123593 FE90_RS06375 WP_002986004.1 1238342..1239268(-) (amiD) [Streptococcus pyogenes strain M23ND]
ATGGAATCGATTGATAAATCTAAATTTCGATTTGTTGAGCGCGATAGTGAAGCCTCCGAAGTGATTGATACCCCTGCTTA
TTCTTACTGGAAATCAGTGTTTCGTCAGTTTTTTTCTAAAAAATCTACAGTCTTTATGCTCGTGATTTTAGTGACAGTCT
TGATGATGAGCTTTATTTATCCAATGTTTGCCAACTACGACTTTAATGACGTTAGTAATATCAATGACTTTTCAAAGCGT
TATATTTGGCCAAATGCAGAGTACTGGTTTGGAACCGACAAAAATGGGCAATCTCTGTTTGATGGTGTTTGGTATGGGGC
ACGTAATTCTATTTTAATCTCAGTTATAGCGACACTAATTAATATCACCATCGGGGTAGTGTTAGGAGCCATATGGGGAG
TTTCTAAAGCATTTGATAAAGTTATGATTGAAATTTATAACATTATCTCAAATATCCCTTCTATGCTTATTATCATTGTT
TTGACCTATTCATTAGGTGCAGGATTTTGGAATTTGATTCTAGCTTTCTGTATCACTGGATGGATTGGTGTCGCCTACTC
CATCCGTGTTCAAATCTTGCGTTACCGTGATTTAGAATACAACCTTGCTAGTCAAACTTTGGGAACACCAATGTACAAGA
TTGCTGTTAAGAACCTGCTGCCTCAATTGGTTTCAGTTATCATGACTATGTTGTCACAAATGCTACCAGTTTATGTATCT
TCTGAGGCCTTCTTATCCTTCTTTGGGATTGGTTTACCAACCACCACTCCAAGTTTAGGACGTTTGATTGCTAATTATTC
AAGCAACTTAACAACAAATGCCTACCTCTTTTGGATTCCCTTAGTAACATTGATTTTAGTATCGTTACCACTATACATTG
TCGGACAAAACTTGGCTGATGCTAGTGACCCACGTTCACATAGATAG

Domains

Predicted by InterproScan.

• N-terminal TM domain of oligopeptide transport permease C (OppC_N) (28-72)

• Binding-protein-dependent transport system inner membrane component (BPD_transp_1) (125-305)

3D structure

• AlphaFold DB: Q1JNF8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiD	Streptococcus salivarius strain HSISS4	73.701	100	0.737
amiD	Streptococcus thermophilus LMG 18311	73.052	100	0.731
amiD	Streptococcus thermophilus LMD-9	73.052	100	0.731