Detailed information NTG0123592

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: FE90_RS06370
• Genome accession: NZ_CP008695
• Coordinates: 1237263..1238333 (-)
• Length: 356 a.a.
• NCBI ID: WP_010921893.1
• Uniprot ID: A0A4U9C068
• Organism: Streptococcus pyogenes strain M23ND
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1232263..1243333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FE90_RS09800 (FE90_1262)	-	1234740..1235033 (+)	294	WP_038433283.1	transposase	-
FE90_RS10140	-	1235177..1235287 (+)	111	WP_238578131.1	IS3 family transposase	-
FE90_RS10145	-	1235265..1235597 (-)	333	Protein_1237	DDE-type integrase/transposase/recombinase	-
FE90_RS10150	-	1235639..1235722 (+)	84	Protein_1238	integrase core domain-containing protein	-
FE90_RS10045 (FE90_1265)	-	1235960..1236199 (+)	240	WP_038433587.1	hypothetical protein	-
FE90_RS10355	-	1236226..1236309 (+)	84	Protein_1240	IS3 family transposase	-
FE90_RS06365 (FE90_1266)	amiF	1236347..1237270 (-)	924	WP_038433588.1	ATP-binding cassette domain-containing protein	Regulator
FE90_RS06370 (FE90_1267)	amiE	1237263..1238333 (-)	1071	WP_010921893.1	ABC transporter ATP-binding protein	Regulator
FE90_RS06375 (FE90_1268)	amiD	1238342..1239268 (-)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
FE90_RS06380 (FE90_1269)	amiC	1239268..1240770 (-)	1503	WP_011017334.1	ABC transporter permease	Regulator
FE90_RS06385 (FE90_1270)	amiA	1240835..1242805 (-)	1971	WP_038433589.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39703.77 Da
• Isoelectric Point: 5.6707

>NTDB_id=123592 FE90_RS06370 WP_010921893.1 1237263..1238333(-) (amiE) [Streptococcus pyogenes strain M23ND]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=123592 FE90_RS06370 WP_010921893.1 1237263..1238333(-) (amiE) [Streptococcus pyogenes strain M23ND]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATTGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: A0A4U9C068

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.667	100	0.775
amiE	Streptococcus thermophilus LMG 18311	75.556	100	0.764
amiE	Streptococcus thermophilus LMD-9	75.556	100	0.764
oppD	Streptococcus mutans UA159	56.677	94.663	0.537