Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   FE90_RS06385 Genome accession   NZ_CP008695
Coordinates   1240835..1242805 (-) Length   656 a.a.
NCBI ID   WP_038433589.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M23ND     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1243039..1244022 1240835..1242805 flank 234


Gene organization within MGE regions


Location: 1240835..1244022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE90_RS06385 (FE90_1270) amiA 1240835..1242805 (-) 1971 WP_038433589.1 peptide ABC transporter substrate-binding protein Regulator
  FE90_RS06390 (FE90_1271) - 1243039..1244022 (+) 984 WP_038433590.1 IS30-like element IS1239 family transposase -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 72088.61 Da        Isoelectric Point: 5.2879

>NTDB_id=123595 FE90_RS06385 WP_038433589.1 1240835..1242805(-) (amiA) [Streptococcus pyogenes strain M23ND]
MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLV
PSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENYWD
AKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKK
DPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGKDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWKDVN
LADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETSTHE
AQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDN
DARYKAYAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVTAKQYEKAKEKWMKAKA
KSNAKYAEKLADHVEK

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=123595 FE90_RS06385 WP_038433589.1 1240835..1242805(-) (amiA) [Streptococcus pyogenes strain M23ND]
ATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGGTAATAAAAA
TGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATTATATTTTGA
CTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGTAATTTAGTA
CCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGTCTCTTGGTA
TACGGCTGATGGTGAAGAATATGCCCCGGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTGACGATAAAT
CAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTTAAAGAAGTT
GGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAAAACAACTTA
TAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCATCATCAATCC
TTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAACTACTGGGAT
GCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAAGAACTTTGA
CAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATGCTGATAACA
TTACTTACGGAATGTTGACTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAACACTAAGAAA
GACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAGTTTGCTTTTGACCG
AGCGTCATTCCAAGCACAAACTGCAGGTAAAGATGCCAAAACAAAAGCCTTACGTAACATGCTTGTGCCACCAACTTTTG
TAACCGTTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGTGATGAATGGAAAGACGTTAAC
TTAGCTGATGCTCAAGATGGTTTCTATAATCCTGAAAAAGCAAAAGTTGAATTTGCAAAAGCCAAAGAAGCTTTGACAGC
TGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAGGCAAACGCAGCAACTGTTCAGGAAGCCCAGTCTT
TCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAAAATGTCATTGTCAATGTTCTTGAAACAGAAACATCAACTCACGAA
GCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATTATTTCATCATGGTGGGGACCAGACTACCAAGA
TCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGCGGATCTGTTATCCAAAAACTTGGAATCAAAGCAGGTCAAA
ATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACCTACCAAACTCTTCTTGATGAAGCAGCAGCAATTACAGACGACAAC
GATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAATGCCGTAGATATTCCAGTTGTGGCATTGGG
TGGCACTCCACGAGTTACTAAAGCCGTTCCATTTAGCGGGGGCTTCTCTTGGGCAGGGTCTAAAGGTCCTCTAGCATATA
AAGGAATGAAACTTCAAGACAAACCTGTCACAGCAAAACAATACGAAAAAGCAAAAGAAAAATGGATGAAAGCAAAGGCT
AAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(79-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

51.286

100

0.517
  amiA3 Streptococcus thermophilus LMG 18311

50

100

0.505
  amiA3 Streptococcus thermophilus LMD-9

49.698

100

0.502

Multiple sequence alignment