Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EN73_RS00940 Genome accession   NZ_CP007632
Coordinates   148911..149666 (+) Length   251 a.a.
NCBI ID   WP_000425371.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NGBS572     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 143911..154666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN73_RS00925 (EN73_00925) - 144346..145896 (-) 1551 WP_000722379.1 ABC transporter substrate-binding protein/permease -
  EN73_RS10830 (EN73_00930) - 146032..147906 (+) 1875 Protein_134 DUF2207 family protein -
  EN73_RS00935 (EN73_00935) - 147952..148791 (+) 840 WP_000905327.1 undecaprenyl-diphosphate phosphatase -
  EN73_RS00940 (EN73_00940) mecA 148911..149666 (+) 756 WP_000425371.1 adaptor protein MecA Regulator
  EN73_RS00945 (EN73_00945) - 149668..150828 (+) 1161 WP_000612110.1 glycosyltransferase family 4 protein -
  EN73_RS00950 (EN73_00950) sufC 150993..151763 (+) 771 WP_000114502.1 Fe-S cluster assembly ATPase SufC -
  EN73_RS00955 (EN73_00955) sufD 151800..153062 (+) 1263 WP_000031276.1 Fe-S cluster assembly protein SufD -
  EN73_RS00960 (EN73_00960) - 153064..154296 (+) 1233 WP_000173346.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29054.91 Da        Isoelectric Point: 4.2155

>NTDB_id=121868 EN73_RS00940 WP_000425371.1 148911..149666(+) (mecA) [Streptococcus agalactiae strain NGBS572]
MEMKQISETTLKITISMEDLEDRGMELKDFLIPQEKTEEFFYSVMDELDLPENFKNSGMLSFRVTPKKDRIDVFVTKSEL
SKDLNLEELADLGDISKMSPEDFFKTLEQSMLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQPEKEVETIGYVHYV
FDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQPSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDD
AISKLQMIEMG

Nucleotide


Download         Length: 756 bp        

>NTDB_id=121868 EN73_RS00940 WP_000425371.1 148911..149666(+) (mecA) [Streptococcus agalactiae strain NGBS572]
ATGGAAATGAAACAAATCAGTGAAACAACACTGAAAATTACAATTAGTATGGAAGATTTAGAAGATCGTGGTATGGAGCT
GAAAGATTTCCTAATCCCTCAGGAGAAGACTGAGGAATTTTTCTATTCTGTCATGGATGAATTAGACTTGCCAGAAAACT
TTAAAAATAGTGGTATGTTAAGTTTTCGAGTAACACCTAAAAAAGATCGCATTGATGTTTTTGTTACAAAGTCTGAATTA
AGTAAAGATTTAAATTTAGAAGAATTAGCAGATTTGGGTGACATTTCAAAAATGTCTCCAGAAGACTTTTTTAAAACATT
GGAACAATCGATGTTGGAAAAAGGGGATACGGATGCCCATGCCAAATTAGCAGAAATTGAAAATATGATGGATAAAGCAA
CTCAAGAAGTAGTTGAGGAAAATGTTTCTGAAGAACAACCTGAAAAGGAAGTAGAAACGATTGGATATGTTCACTATGTC
TTTGATTTTGATAATATTGAAGCTGTAGTTCGATTTTCACAAACGATTGATTTTCCAATAGAAGCTTCTGAACTCTATAA
AAATGGTAAAGGCTATCATATGACAATTTTGCTAGACTTGGAAAACCAACCAAGCTACTTTGCTAATTTGATGTACGCTC
GAATGCTTGAACATGCTAATGTGGGCACAAAAACACGAGCTTACTTGAAAGAGCATAGTATTCAATTGATTCATGATGAT
GCTATTTCAAAATTACAAATGATTGAGATGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.742

98.805

0.669
  mecA Streptococcus thermophilus LMD-9

60.159

100

0.602
  mecA Streptococcus thermophilus LMG 18311

59.363

100

0.594
  mecA Streptococcus pneumoniae Rx1

46.614

100

0.466
  mecA Streptococcus pneumoniae D39

46.614

100

0.466
  mecA Streptococcus pneumoniae R6

46.614

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.614

100

0.466

Multiple sequence alignment