Detailed information NTG0121819

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: EN71_RS01090
• Genome accession: NZ_CP007631
• Coordinates: 188083..189126 (+)
• Length: 347 a.a.
• NCBI ID: WP_223295889.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NGBS061
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	189547..190352	188083..189126	flank	421

Gene organization within MGE regions

Location: 188083..190352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN71_RS01090 (EN72_01115)	comYB	188083..189126 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
EN71_RS01095 (EN72_01120)	comGC/cglC	189123..189452 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
EN71_RS11820	-	189427..189537 (+)	111	Protein_164	competence protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39936.65 Da
• Isoelectric Point: 9.9002

>NTDB_id=121819 EN71_RS01090 WP_223295889.1 188083..189126(+) (comYB) [Streptococcus agalactiae strain NGBS061]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDSMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRNYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGIELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide

• Length: 1044 bp

>NTDB_id=121819 EN71_RS01090 WP_223295889.1 188083..189126(+) (comYB) [Streptococcus agalactiae strain NGBS061]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGTATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGAATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTATTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCCGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (34-150)

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	62.17	98.271	0.611
comYB	Streptococcus mutans UA159	61.877	98.271	0.608
comYB	Streptococcus gordonii str. Challis substr. CH1	56.305	98.271	0.553
comGB/cglB	Streptococcus mitis NCTC 12261	55.224	96.542	0.533
comGB/cglB	Streptococcus mitis SK321	54.627	96.542	0.527
comGB/cglB	Streptococcus pneumoniae Rx1	53.731	96.542	0.519
comGB/cglB	Streptococcus pneumoniae D39	53.731	96.542	0.519
comGB/cglB	Streptococcus pneumoniae R6	53.731	96.542	0.519
comGB/cglB	Streptococcus pneumoniae TIGR4	53.731	96.542	0.519
comGB	Lactococcus lactis subsp. cremoris KW2	50.148	97.118	0.487