Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   SD90_RS00665 Genome accession   NZ_CP010450
Coordinates   104087..104515 (+) Length   142 a.a.
NCBI ID   WP_023605232.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS638     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99087..109515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD90_RS00645 (SD90_00645) - 101418..101783 (+) 366 WP_002986560.1 DUF1033 family protein -
  SD90_RS00650 (SD90_00650) comGA 101876..102814 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  SD90_RS00655 (SD90_00655) comGB 102750..103784 (+) 1035 WP_225793059.1 competence type IV pilus assembly protein ComGB Machinery gene
  SD90_RS00660 (SD90_00660) comGC 103786..104112 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  SD90_RS00665 (SD90_00665) comGD 104087..104515 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD Machinery gene
  SD90_RS00670 (SD90_00670) comGE 104472..104756 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  SD90_RS00675 (SD90_00675) comGF 104749..105183 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  SD90_RS00680 (SD90_00680) comGG 105167..105493 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  SD90_RS00685 (SD90_00685) comGH 105591..106544 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  SD90_RS00690 (SD90_00690) - 106603..107799 (+) 1197 WP_032463122.1 acetate kinase -
  SD90_RS00695 (SD90_00695) - 107985..108293 (+) 309 WP_032463123.1 hypothetical protein -
  SD90_RS00700 (SD90_00700) proC 108376..109146 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16256.99 Da        Isoelectric Point: 10.1022

>NTDB_id=121353 SD90_RS00665 WP_023605232.1 104087..104515(+) (comGD) [Streptococcus pyogenes strain NGAS638]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRCFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=121353 SD90_RS00665 WP_023605232.1 104087..104515(+) (comGD) [Streptococcus pyogenes strain NGAS638]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGATGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

44.961

90.845

0.408
  comGD Streptococcus mutans UA159

44.961

90.845

0.408
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366

Multiple sequence alignment