Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DK43_RS08160 Genome accession   NZ_CP007573
Coordinates   1697755..1698510 (-) Length   251 a.a.
NCBI ID   WP_003028444.1    Uniprot ID   A0AAI9J7E8
Organism   Streptococcus anginosus strain SA1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1692755..1703510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS08140 (DK43_08335) - 1693186..1694418 (-) 1233 WP_037607640.1 cysteine desulfurase -
  DK43_RS08145 (DK43_08340) sufD 1694434..1695696 (-) 1263 WP_037607638.1 Fe-S cluster assembly protein SufD -
  DK43_RS08150 (DK43_08345) sufC 1695736..1696506 (-) 771 WP_037567398.1 Fe-S cluster assembly ATPase SufC -
  DK43_RS08155 (DK43_08350) - 1696598..1697764 (-) 1167 WP_003028442.1 MraY family glycosyltransferase -
  DK43_RS08160 (DK43_08355) mecA 1697755..1698510 (-) 756 WP_003028444.1 adaptor protein MecA Regulator
  DK43_RS08165 (DK43_08360) - 1698634..1699476 (-) 843 WP_003028445.1 undecaprenyl-diphosphate phosphatase -
  DK43_RS08170 (DK43_08365) - 1699543..1701432 (-) 1890 WP_003028446.1 DUF2207 domain-containing protein -
  DK43_RS08175 (DK43_08370) - 1701560..1703125 (+) 1566 WP_003028447.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29061.88 Da        Isoelectric Point: 4.1324

>NTDB_id=121229 DK43_RS08160 WP_003028444.1 1697755..1698510(-) (mecA) [Streptococcus anginosus strain SA1]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMEEQEENSDELTQKYIYYI
LKFSSLKEAIVFSKTVDYAVNTSELYKMDGYYYLTILVDIEGHPKRYPAWLLASMREHAEDTDVTRAVLQEHGYLLLVNE
AVASLKKVKCL

Nucleotide


Download         Length: 756 bp        

>NTDB_id=121229 DK43_RS08160 WP_003028444.1 1697755..1698510(-) (mecA) [Streptococcus anginosus strain SA1]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTTGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAGCGGTATGCTCAGTTTTCGTGTAACTCCTAAACCAGACCGACTGGATGTGTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAATTTTGATGATTTGGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCTGATGAATTTCT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAAGAACAAGAGGAAAATAGTGACGAGCTAACGCAAAAATATATCTATTACATT
TTGAAATTTTCCAGCCTGAAAGAAGCGATTGTCTTTTCTAAAACAGTAGACTATGCTGTTAACACTTCGGAGTTGTACAA
AATGGATGGTTACTATTATTTAACAATCTTGGTTGATATTGAAGGACATCCTAAGCGTTATCCAGCTTGGCTTCTGGCTT
CTATGCGTGAACATGCAGAAGACACAGATGTGACAAGAGCTGTTTTACAAGAGCATGGTTATTTATTGCTTGTCAACGAG
GCAGTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.129

98.805

0.653
  mecA Streptococcus pneumoniae D39

66.129

98.805

0.653
  mecA Streptococcus pneumoniae R6

66.129

98.805

0.653
  mecA Streptococcus pneumoniae TIGR4

65.726

98.805

0.649
  mecA Streptococcus mutans UA159

49.597

98.805

0.49
  mecA Streptococcus thermophilus LMD-9

45.882

100

0.466
  mecA Streptococcus thermophilus LMG 18311

45.49

100

0.462

Multiple sequence alignment