Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DK43_RS08000 Genome accession   NZ_CP007573
Coordinates   1660675..1662549 (-) Length   624 a.a.
NCBI ID   WP_003028410.1    Uniprot ID   -
Organism   Streptococcus anginosus strain SA1     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1655675..1667549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS07970 (DK43_08160) - 1655831..1656148 (+) 318 WP_003043378.1 DUF960 domain-containing protein -
  DK43_RS07975 (DK43_08165) - 1656277..1656648 (-) 372 WP_003028404.1 S1 RNA-binding domain-containing protein -
  DK43_RS07980 (DK43_08170) - 1656650..1658050 (-) 1401 WP_003028405.1 Cof-type HAD-IIB family hydrolase -
  DK43_RS07985 (DK43_08175) - 1658090..1658722 (-) 633 WP_003028406.1 response regulator transcription factor -
  DK43_RS07990 (DK43_08180) - 1658724..1659719 (-) 996 WP_003028408.1 sensor histidine kinase -
  DK43_RS07995 (DK43_08185) liaF 1659716..1660414 (-) 699 WP_003028409.1 cell wall-active antibiotics response protein LiaF -
  DK43_RS08000 (DK43_08190) stkP 1660675..1662549 (-) 1875 WP_003028410.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DK43_RS08005 (DK43_08195) - 1662546..1663286 (-) 741 WP_022525304.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DK43_RS08010 (DK43_08200) rsmB 1663304..1664617 (-) 1314 WP_022525305.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DK43_RS08015 (DK43_08205) fmt 1664607..1665542 (-) 936 WP_003028413.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67632.65 Da        Isoelectric Point: 9.3373

>NTDB_id=121227 DK43_RS08000 WP_003028410.1 1660675..1662549(-) (stkP) [Streptococcus anginosus strain SA1]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPAPTKEVVS
STPTPTPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTP
AAGSSYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQNPEAGQS
LNLKSDRIVLYVYEPKTEDSSTSESSSQSDSSSGKTSPSSSSSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=121227 DK43_RS08000 WP_003028410.1 1660675..1662549(-) (stkP) [Streptococcus anginosus strain SA1]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAGAATCATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCGGTTAAGGTTCTAAGAACCAATTACCAGACAGATCCGATTG
CTGTAGCACGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATAATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCATACGCATGGGATTGTTC
ACCGTGATTTAAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACAGACTTTGGGATTGCAGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGTTGGGATCTGTACATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACACATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAACATTTCCAAAAGCCCCTACCGTCCATTATTGCTGAAAATCCAAACGTTCCA
CAAGCATTGGAAAATGTAGTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGTTTATCTGCTGACCGTCGAAATGAGAAAAAGCTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTGCTCCTACAAAAGAAGTAGTCAGT
AGTACGCCTACGCCTACGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCGGTGGT
TTTAGTCATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCTCTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAAACCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTGATAGTAGCTCAGGTAAAACTAGCCCATCCTCTAGTAGTTCGTCAACTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(364-427)

PASTA domain (PASTA)

(433-500)

PASTA domain (PASTA)

(505-573)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.812

93.75

0.617
  stkP Streptococcus pneumoniae D39

65.47

93.75

0.614
  stkP Streptococcus pneumoniae R6

65.47

93.75

0.614
  stkP Streptococcus pneumoniae Rx1

65.299

93.75

0.612
  pknB Streptococcus mutans UA159

58.803

93.75

0.551
  stkP/pknB Streptococcus salivarius strain HSISS4

54.959

98.558

0.542

Multiple sequence alignment