Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DK43_RS07235 Genome accession   NZ_CP007573
Coordinates   1510062..1512215 (+) Length   717 a.a.
NCBI ID   WP_133162782.1    Uniprot ID   -
Organism   Streptococcus anginosus strain SA1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1505062..1517215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS07210 (DK43_07390) arcA 1505090..1506319 (-) 1230 WP_003028185.1 arginine deiminase -
  DK43_RS07215 (DK43_07395) - 1506629..1507315 (-) 687 WP_003028187.1 Crp/Fnr family transcriptional regulator -
  DK43_RS07220 (DK43_07400) - 1507449..1508504 (-) 1056 WP_022525371.1 serine hydrolase -
  DK43_RS07225 (DK43_07405) - 1508719..1509048 (-) 330 WP_003028191.1 hypothetical protein -
  DK43_RS07230 (DK43_07410) - 1509100..1509351 (-) 252 WP_022525199.1 hypothetical protein -
  DK43_RS10170 - 1509533..1509760 (-) 228 WP_231466403.1 bacteriocin immunity protein -
  DK43_RS07235 (DK43_07415) comA/nlmT 1510062..1512215 (+) 2154 WP_133162782.1 peptide cleavage/export ABC transporter Regulator
  DK43_RS07240 (DK43_07420) - 1512226..1513587 (+) 1362 WP_003028197.1 bacteriocin secretion accessory protein -
  DK43_RS07245 (DK43_07425) - 1513861..1514466 (-) 606 WP_022525198.1 superoxide dismutase -
  DK43_RS07250 (DK43_07430) holA 1514537..1515574 (-) 1038 WP_003028201.1 DNA polymerase III subunit delta -
  DK43_RS07255 (DK43_07435) cvfB 1515656..1516510 (-) 855 WP_003028203.1 RNA-binding virulence regulatory protein CvfB -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80726.12 Da        Isoelectric Point: 9.0519

>NTDB_id=121220 DK43_RS07235 WP_133162782.1 1510062..1512215(+) (comA/nlmT) [Streptococcus anginosus strain SA1]
MVNFKKSFVPQIDARDCGIAALASIARYYDSNYSLAHLRELAKTDKEGTTALGIVKAAKEMGFETRPIQADMTLFDTEEL
PYPFIVHVNKNGNLQHYYVVYKNEKKHLLIGDPDPTVKITKISKEQFVKDWTGVAIFLAPKPSYEPHKDKKNELASFLPL
IFKQRSLIFYIVLASLLVTLINIVGSYYLQGVLDEYIPNQMKSTLGIISIGLIIAYILQQMMSFSRDYLLTVLSQRLTID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSIVMIVGNVLLLQNTNLFLLTLLAIPIYAL
IIFAFMKPFEKMNNDVMQSNAMVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKTFKLSKYSIMQTALKQGAQL
ILNVVILWVGASLVMSQKISIGQLITFNTLLSYFTSPLESIINLQTKLQSAKVANHRLNEVYLVESEFKTKQVLTEKKFL
AGDITFHNVSYKYGFGRDILSDISLTIKKGDKISLVGVSGSGKTTLAKMIVHFYEPYQGQIRLNGNDLKTIDKKVLRQYI
NYLPQQAYIFSGSILDNLTLGADQTVSQSDILRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRITLARALLTKSP
ILILDEATSGLDVLTEKKVIDNLMKLPDKTIIFVAHHLSISKRTNQIIVLDQGKVIETGSHTELIGRKGFYYHLFNK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=121220 DK43_RS07235 WP_133162782.1 1510062..1512215(+) (comA/nlmT) [Streptococcus anginosus strain SA1]
ATAGTGAATTTTAAAAAATCATTTGTTCCGCAAATAGATGCTAGAGATTGTGGTATTGCTGCTCTGGCTTCCATTGCTAG
ATACTATGATTCAAATTATTCTTTAGCACACTTGAGAGAGCTCGCAAAGACAGACAAAGAAGGGACAACTGCACTTGGAA
TTGTCAAAGCAGCAAAAGAAATGGGCTTTGAAACCCGACCAATCCAAGCAGACATGACATTGTTTGATACAGAAGAGCTT
CCCTATCCTTTCATCGTACATGTCAACAAGAATGGCAATCTTCAGCACTATTATGTCGTTTATAAAAACGAGAAAAAGCA
CTTGCTTATCGGTGATCCTGATCCAACTGTCAAAATAACTAAGATTAGCAAAGAACAATTTGTAAAAGATTGGACTGGTG
TTGCTATCTTTCTCGCACCGAAACCTAGCTATGAACCTCATAAGGATAAGAAGAACGAGCTTGCTAGCTTTTTACCACTC
ATCTTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTCGTGACCCTCATCAACATTGTGGGCTCCTA
TTATCTGCAAGGTGTTTTGGACGAATACATCCCAAATCAGATGAAATCAACTCTTGGGATTATTTCAATTGGGCTTATCA
TTGCCTACATCTTACAGCAAATGATGAGTTTTTCAAGAGACTACCTGCTAACAGTGCTCAGTCAACGATTAACAATTGAT
GTGATTTTGTCTTATATTCGGCATATTTTTGAATTACCAATGTCCTTTTTTGCGACGAGACGCACTGGGGAGATTATTTC
TCGTTTTACAGATGCCAACTCCATTATTGATGCTCTAGCTTCAACTATCCTGTCTCTCTTTCTTGATTTGTCCATTGTGA
TGATTGTCGGCAATGTTCTTTTACTGCAAAATACCAATCTCTTTTTACTCACCTTGCTTGCAATTCCTATCTACGCTCTC
ATTATTTTTGCTTTTATGAAGCCTTTTGAAAAAATGAATAACGATGTTATGCAAAGCAATGCTATGGTAAATTCTGCCAT
TATCGAAGATATCAACGGAATTGAAACCATTAAATCTTTAACCAGCGAAGAAAGCCGTTACCAAAAGATTGATAGCGAGT
TTGTTGATTATCTGGATAAGACTTTCAAATTAAGTAAATATTCCATTATGCAAACAGCTCTCAAACAAGGAGCACAACTT
ATTTTGAATGTGGTCATTCTCTGGGTTGGAGCTTCTTTAGTCATGTCTCAAAAGATTTCAATTGGTCAGCTGATTACTTT
CAATACTCTCCTTTCATACTTTACTAGTCCACTTGAAAGTATCATCAATCTTCAAACCAAACTGCAATCAGCTAAAGTTG
CCAATCATCGACTGAATGAAGTTTATCTGGTAGAATCCGAATTCAAAACCAAGCAAGTCCTTACGGAGAAAAAATTCTTA
GCTGGAGATATTACTTTCCATAACGTCTCCTATAAATACGGATTTGGACGAGATATTTTATCAGATATTAGTTTGACTAT
CAAGAAGGGAGATAAAATTAGTCTTGTTGGCGTCAGCGGTTCGGGAAAAACAACACTTGCTAAGATGATTGTTCATTTTT
ATGAGCCTTATCAAGGACAAATTCGCCTCAATGGAAATGACCTCAAGACAATTGATAAGAAAGTTCTTCGGCAATATATC
AACTACTTACCTCAGCAAGCTTACATCTTTAGTGGTTCCATTCTAGACAACCTCACATTAGGAGCCGATCAAACAGTTTC
TCAATCAGATATTCTTCGTGCCTGTGAAATTGCAGAAATTCGTTCAGATATCGAACAAATGCCCATGGGATACCAGACAG
AATTGTCTGACGGAGCTGGATTATCTGGTGGACAAAAGCAACGAATTACACTTGCACGCGCTCTGCTGACGAAATCTCCC
ATTCTCATTTTAGATGAAGCAACGAGTGGATTAGATGTTCTAACAGAGAAAAAAGTCATTGATAATCTCATGAAATTACC
CGACAAAACCATTATTTTTGTTGCTCATCACCTCAGCATTTCAAAGCGTACAAATCAGATTATTGTCCTTGACCAAGGAA
AAGTGATTGAAACTGGTTCTCATACTGAATTGATAGGAAGAAAAGGTTTTTATTATCATCTATTTAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-649)

ABC transporter transmembrane region (ABC_membrane)

(168-438)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.355

98.884

0.715
  comA Streptococcus mitis NCTC 12261

66.76

99.442

0.664
  comA Streptococcus mitis SK321

66.339

99.442

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

66.199

99.442

0.658
  comA Streptococcus pneumoniae D39

65.919

99.442

0.656
  comA Streptococcus pneumoniae R6

65.919

99.442

0.656
  comA Streptococcus pneumoniae Rx1

65.919

99.442

0.656
  comA Streptococcus pneumoniae TIGR4

65.498

99.442

0.651

Multiple sequence alignment