Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   DK43_RS00120 Genome accession   NZ_CP007573
Coordinates   24435..25760 (+) Length   441 a.a.
NCBI ID   WP_218015592.1    Uniprot ID   -
Organism   Streptococcus anginosus strain SA1     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 19435..30760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS00090 (DK43_00095) dnaA 19734..21077 (-) 1344 WP_003029515.1 chromosomal replication initiator protein DnaA -
  DK43_RS00095 (DK43_00100) spo0J 21305..22072 (-) 768 WP_003029516.1 ParB/RepB/Spo0J family partition protein Regulator
  DK43_RS00100 (DK43_00105) htrA 22127..23317 (-) 1191 WP_003029517.1 trypsin-like peptidase domain-containing protein Regulator
  DK43_RS00105 (DK43_00110) rlmH 23510..23989 (+) 480 WP_003029518.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DK43_RS09895 (DK43_00120) - 24271..24417 (+) 147 WP_003029519.1 bacteriocin -
  DK43_RS00120 (DK43_00125) comD/comD2 24435..25760 (+) 1326 WP_218015592.1 GHKL domain-containing protein Regulator
  DK43_RS00125 (DK43_00130) comE 25760..26509 (+) 750 WP_003029521.1 competence system response regulator transcription factor ComE Regulator
  DK43_RS09900 (DK43_00145) - 26978..27811 (+) 834 WP_022525263.1 ISL3 family transposase -
  DK43_RS00145 (DK43_00150) - 27855..30431 (-) 2577 WP_003027897.1 YfhO family protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 52091.87 Da        Isoelectric Point: 8.9107

>NTDB_id=121185 DK43_RS00120 WP_218015592.1 24435..25760(+) (comD/comD2) [Streptococcus anginosus strain SA1]
MVKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKV
KKHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKADFKENIVQ
LNFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVNLY
NEIRGFRHDYGGMLASFQSAIHTSNIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGE
GRGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=121185 DK43_RS00120 WP_218015592.1 24435..25760(+) (comD/comD2) [Streptococcus anginosus strain SA1]
ATTGTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATACTGCTATAAGAAAAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTTAACTGATTTCACTACTTTAA
TACATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTT
AAAAAACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATCATTTCTTTAGTTT
TTATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTTAAAGAGAATATTGTGCAA
TTAAACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTGTCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATG
AAAAAGAAGAACAAATTAAACAGAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATTGTTAATCTGTAT
AATGAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAAGTAATATAAA
AGAAGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTTCTTTTGAA
TAATGCCATAGAAGGATCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCT
TAGTCATTCAAAATTCACGTAAGAAAAGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAA
GGACGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGA
TGAATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

53.846

100

0.54
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.11

99.32

0.537
  comD Streptococcus mitis SK321

47.449

88.889

0.422
  comD Streptococcus mitis NCTC 12261

48.67

85.261

0.415
  comD/comD2 Streptococcus pneumoniae TIGR4

48.404

85.261

0.413
  comD/comD1 Streptococcus pneumoniae Rx1

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae D39

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae R6

47.872

85.261

0.408

Multiple sequence alignment