Detailed information NTG0120896

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DK92_RS04210
• Genome accession: NZ_CP007561
• Coordinates: 858286..859122 (-)
• Length: 278 a.a.
• NCBI ID: WP_047235811.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS596
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 853286..864122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK92_RS04190 (DK92_04305)	-	853506..854498 (-)	993	WP_047235809.1	D-lactate dehydrogenase	-
DK92_RS04195 (DK92_04310)	-	854513..855079 (-)	567	Protein_772	PTS sugar transporter subunit IIC	-
DK92_RS09275	-	855119..855976 (+)	858	Protein_773	LysR family transcriptional regulator	-
DK92_RS04205 (DK92_04320)	topA	856051..858180 (-)	2130	WP_047235810.1	type I DNA topoisomerase	-
DK92_RS04210 (DK92_04325)	dprA	858286..859122 (-)	837	WP_047235811.1	DNA-processing protein DprA	Machinery gene
DK92_RS04215 (DK92_04330)	-	859187..859978 (-)	792	WP_002995007.1	ribonuclease HII	-
DK92_RS04220 (DK92_04335)	ylqF	859968..860816 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DK92_RS04225 (DK92_04340)	-	861035..861475 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DK92_RS04230 (DK92_04345)	trhA	861472..862122 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DK92_RS04235 (DK92_04350)	-	862239..863150 (+)	912	WP_047235812.1	diacylglycerol/lipid kinase family protein	-
DK92_RS04240 (DK92_04355)	-	863200..863574 (-)	375	WP_047235813.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30993.02 Da
• Isoelectric Point: 9.2511

>NTDB_id=120896 DK92_RS04210 WP_047235811.1 858286..859122(-) (dprA) [Streptococcus pyogenes strain NGAS596]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIISGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=120896 DK92_RS04210 WP_047235811.1 858286..859122(-) (dprA) [Streptococcus pyogenes strain NGAS596]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTATTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGCCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568