Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CF65_RS00545 Genome accession   NZ_CP007502
Coordinates   114926..116149 (+) Length   407 a.a.
NCBI ID   WP_025298077.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans HK1651     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109926..121149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CF65_RS00525 (CF65_00153) nanQ 111425..111895 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  CF65_RS00530 (CF65_00158) ampD 112369..112923 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CF65_RS00535 (CF65_00160) pilA 113045..113497 (+) 453 WP_005586498.1 pilin Machinery gene
  CF65_RS00540 (CF65_00161) pilB 113524..114933 (+) 1410 WP_019518272.1 GspE/PulE family protein Machinery gene
  CF65_RS00545 (CF65_00162) pilC 114926..116149 (+) 1224 WP_025298077.1 type II secretion system F family protein Machinery gene
  CF65_RS00550 (CF65_00163) - 116146..116835 (+) 690 WP_005547547.1 prepilin peptidase -
  CF65_RS00555 (CF65_00164) coaE 116885..117508 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  CF65_RS00560 (CF65_00165) yacG 117498..117710 (+) 213 WP_005567966.1 DNA gyrase inhibitor YacG -
  CF65_RS00565 (CF65_00166) - 117710..117982 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  CF65_RS00570 (CF65_00167) - 118379..119752 (+) 1374 WP_005547554.1 alanine/glycine:cation symporter family protein -
  CF65_RS00575 (CF65_00168) raiA 119980..120303 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  CF65_RS00580 (CF65_00169) - 120452..121006 (+) 555 WP_005540709.1 DUF5358 domain-containing protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45944.46 Da        Isoelectric Point: 10.2664

>NTDB_id=120049 CF65_RS00545 WP_025298077.1 114926..116149(+) (pilC) [Aggregatibacter actinomycetemcomitans HK1651]
MIKLKLFQRRAVNRLQQKQKGLIVAETEAMAQQQLLSCGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLQAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQGYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSHSLFLMLQAGIPLNQALQSFLPKQQSWQTKPQQQGDWLLIAGVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=120049 CF65_RS00545 WP_025298077.1 114926..116149(+) (pilC) [Aggregatibacter actinomycetemcomitans HK1651]
ATGATTAAATTGAAACTGTTTCAACGGCGCGCCGTTAATCGACTACAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGCGATGGCACAACAACAGCTGCTTTCATGCGGGTTGCAAAACATCAAATTACAACAAAACTGGCAATTTAGCCACA
AACCGAAAAATGCCGACATCTGCACGCTGCTTTCCCAACTGGCGACGCTGTTACAAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTAGCATTTTCTCAAGCATTGGAACAACAAGGTTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTTTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGGTTATTGGTTCGCGCTGCTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGCTACTTAATCGTATCGTACAACTCTCCCGTTTAGTGGGATT
CAGTCACAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTACAATCTTTCCTACCGAAACAACAAA
GCTGGCAAACTAAACCGCAGCAGCAAGGGGATTGGCTGCTTATTGCGGGAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAACAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAATTGGATCACCAAATCGATCTACTGTCAC
AAATGCTGGAACCGTTGTTGATGGTAATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTACAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

63.275

99.017

0.627
  pilC Haemophilus influenzae 86-028NP

62.531

99.017

0.619
  pilC Glaesserella parasuis strain SC1401

39.152

98.526

0.386

Multiple sequence alignment