Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DYB47_RS01200 Genome accession   NZ_UHFV01000002
Coordinates   196926..197648 (+) Length   240 a.a.
NCBI ID   WP_003080418.1    Uniprot ID   G5JVB2
Organism   Streptococcus macacae NCTC 11558     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 191926..202648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS01185 (NCTC11558_00239) - 192228..193781 (-) 1554 WP_003080093.1 ABC transporter substrate-binding protein/permease -
  DYB47_RS01190 (NCTC11558_00240) - 193929..195824 (+) 1896 WP_003082365.1 DUF2207 domain-containing protein -
  DYB47_RS01195 (NCTC11558_00241) - 195899..196741 (+) 843 WP_003078591.1 undecaprenyl-diphosphate phosphatase -
  DYB47_RS01200 (NCTC11558_00242) mecA 196926..197648 (+) 723 WP_003080418.1 adaptor protein MecA Regulator
  DYB47_RS01205 (NCTC11558_00243) - 197654..198814 (+) 1161 WP_040841657.1 glycosyltransferase family 4 protein -
  DYB47_RS01210 (NCTC11558_00244) sufC 198890..199660 (+) 771 WP_003080743.1 Fe-S cluster assembly ATPase SufC -
  DYB47_RS01215 (NCTC11558_00245) sufD 199696..200958 (+) 1263 WP_003081781.1 Fe-S cluster assembly protein SufD -
  DYB47_RS01220 (NCTC11558_00246) - 200963..202192 (+) 1230 WP_003079905.1 cysteine desulfurase -
  DYB47_RS01225 (NCTC11558_00247) sufU 202179..202619 (+) 441 WP_003082216.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27975.47 Da        Isoelectric Point: 4.1545

>NTDB_id=1171288 DYB47_RS01200 WP_003080418.1 196926..197648(+) (mecA) [Streptococcus macacae NCTC 11558]
MKMKQISETTLKITISMEDLEERGMELKDFLVPQEKTEEFFYAVMDELELPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFEDISKMSPEDFFKTLEETMREKGDAEALDRLAEAEKQDEESADKEQPEERENLDYIHFVLDFPNVQSA
VNFAKTVDYEVEASEFFKSQDAYHMTILLNLENKPDYYADLIFAKMLEHADKGTKTRAYLLEHGVQIMVSDALKELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1171288 DYB47_RS01200 WP_003080418.1 196926..197648(+) (mecA) [Streptococcus macacae NCTC 11558]
ATGAAAATGAAACAAATCAGTGAGACAACACTAAAAATCACTATCAGTATGGAAGATTTAGAAGAAAGAGGAATGGAATT
AAAAGATTTTTTAGTTCCGCAAGAAAAAACAGAAGAATTTTTCTATGCTGTTATGGATGAATTGGAGCTGCCGGAGAATT
TTAAAGACAGCGGTATGCTGAGCTTTAGGGTGACACCAAGAAATGATAGAATTGATGTTTTTGTGACGAAATCAGAGATC
AATAAAAACCTCAATCTCGAAGATTTATCAGATTTTGAGGATATTTCAAAAATGTCACCGGAAGATTTTTTTAAAACTTT
AGAAGAGACGATGCGTGAAAAAGGGGATGCAGAAGCGCTTGACAGGCTGGCGGAAGCTGAAAAGCAAGATGAAGAGAGTG
CTGACAAGGAGCAGCCTGAAGAAAGAGAAAATTTGGATTATATCCATTTTGTTCTTGATTTTCCTAATGTCCAATCAGCA
GTAAATTTTGCCAAAACAGTAGATTATGAGGTAGAAGCTTCTGAGTTTTTTAAGTCGCAAGATGCTTATCATATGACTAT
TTTGTTGAATCTTGAAAATAAACCTGATTATTATGCCGATTTAATCTTTGCAAAGATGCTGGAACATGCTGATAAGGGAA
CAAAGACACGTGCCTATCTCTTAGAGCATGGCGTTCAAATCATGGTGTCAGATGCCTTAAAAGAATTACAAATGATTGGA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JVB2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

82.917

100

0.829
  mecA Streptococcus thermophilus LMD-9

56.967

100

0.579
  mecA Streptococcus thermophilus LMG 18311

56.557

100

0.575
  mecA Streptococcus pneumoniae Rx1

52.245

100

0.533
  mecA Streptococcus pneumoniae D39

52.245

100

0.533
  mecA Streptococcus pneumoniae R6

52.245

100

0.533
  mecA Streptococcus pneumoniae TIGR4

52.245

100

0.533

Multiple sequence alignment