Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACLV7W_RS01815 Genome accession   NZ_OZ217346
Coordinates   372561..374462 (+) Length   633 a.a.
NCBI ID   WP_411865331.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 367561..379462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS01800 (SMID22_03660) fmt 369568..370503 (+) 936 WP_141230963.1 methionyl-tRNA formyltransferase -
  ACLV7W_RS01805 (SMID22_03670) rsmB 370496..371809 (+) 1314 WP_411865330.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACLV7W_RS01810 (SMID22_03680) - 371824..372564 (+) 741 WP_049511028.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACLV7W_RS01815 (SMID22_03690) stkP 372561..374462 (+) 1902 WP_411865331.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACLV7W_RS01820 (SMID22_03700) - 374551..375309 (+) 759 WP_020903004.1 threonine/serine exporter family protein -
  ACLV7W_RS01825 (SMID22_03710) - 375311..375760 (+) 450 WP_020901615.1 threonine/serine exporter family protein -
  ACLV7W_RS01830 (SMID22_03720) - 375874..377046 (+) 1173 WP_261029122.1 hydroxymethylglutaryl-CoA synthase -
  ACLV7W_RS01835 (SMID22_03730) - 377046..378320 (+) 1275 WP_411865332.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ACLV7W_RS01840 (SMID22_03740) - 378356..379321 (-) 966 WP_261029124.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69208.65 Da        Isoelectric Point: 9.5071

>NTDB_id=1170428 ACLV7W_RS01815 WP_411865331.1 372561..374462(+) (stkP) [Streptococcus mitis isolate S. mitis D22]
MIQIGKIFAGRYRILKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSNNRRNEPKLVFDDATKADTKTLPKVPQSTLTSIPKVQTQSPKPQTA
KPSQQVSEDNYATKPVKKRKFRVRYMILLASIVLVAASLIWILSRTPATIAIPNVAGQTVAEAKEILKKANFEIGEEKSE
ASEKVEEGRIIRTDPEAGTGRKEGTKINLVVSSGKQSFQLSNYIGRKSTDVIAELKQKKVPENLIKIEEEESSESEEGTV
LRQSPSAGTTYDLSKASTITLTIAKKVTSVVMPSYTGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPSGTAEGTVVEQSP
RAGEKVDLNKTRIKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRGDTHSTNQSSSEGSHENSRN

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=1170428 ACLV7W_RS01815 WP_411865331.1 372561..374462(+) (stkP) [Streptococcus mitis isolate S. mitis D22]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTCTCAAACAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCTAAAGATTTGATTCTAGACGGGGAAGAAGTGGCGGTAAAGGTCCTGAGGACCAACTACCAGACAGACCCGATTG
CTGTGGCTCGTTTTCAGCGGGAAGCGAGAGCCATGGCAGATTTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTCGCAATGGAATATGTTGCTGGATTAGACCTCAAACGCTATATCAAGGAACATCACCC
TCTTTCAAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTCTTGGCTATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACAGGGATTTGAAACCGCAAAATATCCTTTTGACCCCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCAGTAGCC
TTTGCAGAGACGAGTCTAACTCAGACCAACTCAATGCTAGGTTCTGTGCATTATTTATCACCAGAGCAGGCGCGTGGTTC
TAAAGCAACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTACGATG
GGGATAGCGCAGTGACCATCGCCCTCCAGCATTTCCAGAAACCACTGCCATCGGTTATAGCCGAAAATCCATCTGTGCCT
CAGGCTCTAGAAAATGTTGTTATCAAGGCAACTGCTAAGAAATTGACAGATCGCTACAAATCAGTCGCTGAAATGTATGT
GGATTTGTCGAGTAGTTTGTCTAATAATCGTCGTAATGAACCAAAGCTAGTCTTTGACGATGCAACTAAGGCAGATACTA
AAACTCTTCCAAAAGTTCCACAAAGTACTTTGACCTCGATTCCTAAGGTGCAAACACAAAGTCCAAAGCCACAGACTGCG
AAGCCGAGTCAGCAGGTTTCAGAGGACAATTACGCAACCAAGCCTGTTAAGAAACGGAAATTTAGAGTTCGCTATATGAT
TTTGTTGGCCAGCATTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCGAGAACTCCTGCAACCATTGCCATTCCAA
ATGTGGCAGGTCAGACAGTGGCGGAAGCCAAGGAAATCCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAATCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGAAGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGTAAGCAATCTTTCCAATTGAGCAATTATATCGGCCGTAAATCGACCGATGTTATCGCAG
AACTCAAGCAGAAGAAGGTACCTGAAAATCTCATCAAGATAGAGGAAGAAGAATCAAGCGAGAGTGAAGAAGGAACAGTT
CTTAGACAGAGCCCATCTGCTGGAACAACTTATGATTTGAGTAAGGCCTCAACAATTACTTTAACTATTGCTAAGAAAGT
AACAAGTGTTGTCATGCCAAGTTATACAGGTTCCAGTCTTGAATTTACGAAAAATAACCTCATCCAAATTGTTGGTATAA
AAGAAGCCAACATTGAAGTTGTAGAAGTTACCACAGCTCCTTCCGGAACTGCTGAAGGTACCGTCGTTGAACAGAGTCCA
AGAGCAGGTGAAAAGGTAGATTTGAATAAGACACGCATCAAGATTTCAATTTACAAACCAAAAACACCGCCGTCAACATC
ATCATCAGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACAACACCAAGTCAGGGGAACCAGCAAGGAAATCAACGAG
GAGATACTCATTCTACTAATCAATCAAGTAGTGAGGGAAGCCACGAAAATTCACGTAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

80.034

92.575

0.741
  stkP Streptococcus pneumoniae D39

79.693

92.575

0.738
  stkP Streptococcus pneumoniae R6

79.693

92.575

0.738
  stkP Streptococcus pneumoniae Rx1

79.522

92.575

0.736
  stkP/pknB Streptococcus salivarius strain HSISS4

55.155

91.943

0.507
  pknB Streptococcus mutans UA159

55.268

91.469

0.506

Multiple sequence alignment