Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   ACLV7W_RS00105 Genome accession   NZ_OZ217346
Coordinates   20483..20719 (+) Length   78 a.a.
NCBI ID   WP_194251552.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 15483..25719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS00105 (SMID22_00180) comW 20483..20719 (+) 237 WP_194251552.1 sigma(X)-activator ComW Regulator
  ACLV7W_RS00110 (SMID22_00190) - 20951..22237 (+) 1287 WP_153210200.1 adenylosuccinate synthase -
  ACLV7W_RS00115 (SMID22_00210) tadA 22437..22904 (+) 468 WP_153210198.1 tRNA adenosine(34) deaminase TadA -
  ACLV7W_RS00125 (SMID22_00220) - 23090..23533 (+) 444 WP_000701987.1 dUTP diphosphatase -
  ACLV7W_RS00130 (SMID22_00230) - 23493..24050 (+) 558 WP_411865215.1 histidine phosphatase family protein -
  ACLV7W_RS00135 (SMID22_00240) radA 24064..25425 (+) 1362 WP_077804517.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9871.28 Da        Isoelectric Point: 5.5571

>NTDB_id=1170409 ACLV7W_RS00105 WP_194251552.1 20483..20719(+) (comW) [Streptococcus mitis isolate S. mitis D22]
MLQSIYDQMTDFYDSIEEEYATFFDNSWEWEHFHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLIMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1170409 ACLV7W_RS00105 WP_194251552.1 20483..20719(+) (comW) [Streptococcus mitis isolate S. mitis D22]
ATGCTACAAAGTATCTATGATCAGATGACTGATTTCTATGACAGTATCGAAGAAGAGTATGCTACTTTCTTTGATAATAG
TTGGGAGTGGGAACATTTTCATTTTAAATTTTTGATTTATTATTTAGTTCGATATGGCATTGGGTGTCGTAGGGATTTTA
TTGTTTATCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGATAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

80.769

100

0.808

  comW Streptococcus pneumoniae D39

80.769

100

0.808

  comW Streptococcus pneumoniae R6

80.769

100

0.808

  comW Streptococcus pneumoniae TIGR4

80.769

100

0.808

  comW Streptococcus mitis SK321

74.359

100

0.744

  comW Streptococcus mitis NCTC 12261

74.026

98.718

0.731


Multiple sequence alignment