Detailed information NTG1170375

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACLV7D_RS06360
• Genome accession: NZ_OZ217345
• Coordinates: 1298108..1300348 (-)
• Length: 746 a.a.
• NCBI ID: WP_218764117.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis F22
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1293108..1305348

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7D_RS06325 (SMIF22_12400)	-	1293965..1294345 (-)	381	WP_218764121.1	VOC family protein	-
ACLV7D_RS06330 (SMIF22_12410)	rplT	1294404..1294763 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
ACLV7D_RS06335 (SMIF22_12420)	rpmI	1294815..1295015 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
ACLV7D_RS06340 (SMIF22_12430)	infC	1295048..1295578 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
ACLV7D_RS06345 (SMIF22_12450)	-	1295886..1297067 (-)	1182	WP_218764120.1	hypothetical protein	-
ACLV7D_RS06350 (SMIF22_12460)	-	1297071..1297658 (-)	588	WP_218764119.1	ATP-binding cassette domain-containing protein	-
ACLV7D_RS06355 (SMIF22_12470)	-	1297691..1297879 (-)	189	WP_411865970.1	hypothetical protein	-
ACLV7D_RS06360 (SMIF22_12480)	comEC/celB	1298108..1300348 (-)	2241	WP_218764117.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACLV7D_RS06365 (SMIF22_12490)	comEA/celA/cilE	1300332..1300982 (-)	651	WP_218764116.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACLV7D_RS06370 (SMIF22_12500)	-	1301050..1301619 (-)	570	WP_218764115.1	GNAT family N-acetyltransferase	-
ACLV7D_RS06375 (SMIF22_12510)	ald	1301791..1302903 (+)	1113	WP_112443604.1	alanine dehydrogenase	-
ACLV7D_RS06380 (SMIF22_12520)	-	1302960..1303955 (-)	996	WP_218764114.1	PhoH family protein	-
ACLV7D_RS06385 (SMIF22_12530)	-	1304040..1304255 (-)	216	WP_001232085.1	YozE family protein	-
ACLV7D_RS06390 (SMIF22_12540)	cvfB	1304264..1305118 (-)	855	WP_218764113.1	RNA-binding virulence regulatory protein CvfB	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84613.75 Da
• Isoelectric Point: 9.0595

>NTDB_id=1170375 ACLV7D_RS06360 WP_218764117.1 1298108..1300348(-) (comEC/celB) [Streptococcus mitis isolate S. mitis F22]
MLQWIKNIPIPLIYLSFLLLWLYYAIFSSSYLALLGFVFLLVCLFIQFPWKSAGKALIICGIFGFWFLFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSDGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKVGSWDVGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFSLTVLVLFII
MSNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVVRESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFAFSFLYPVIQLNFIFEWLEEIIRLVSQVASRPLVFGQPNAWLLVLLLISLALVYDLRKNIKRLAVLSLLIIGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEKWQEKTTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKEFVAELQATQTKVRSITAGETLQIFGSQLEVLSPRKIGDGDHEDSLVLYGKL
LDKNFLFTGNLEEKGEKDLLKHYPDLEVDVLKASQHGSKNSSSSAFLEQFKPEMTLISVGKNNRTKLPHQETLTRLETIN
SKVYRTDQQGAIRFKGWNSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1170375 ACLV7D_RS06360 WP_218764117.1 1298108..1300348(-) (comEC/celB) [Streptococcus mitis isolate S. mitis F22]
ATGTTACAGTGGATTAAGAACATCCCCATTCCTCTAATTTATCTGAGTTTTCTGTTGCTTTGGCTTTACTACGCCATTTT
CTCATCATCTTATCTCGCACTGCTAGGTTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGCTCTAATAATTTGTGGAATCTTTGGTTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
TTGGCGGATTCTGTTGAGAGGGTACGGATTTTGCCTGACACTATTAAGGTCAATGGTGATAGTCTGTCCTTTCGTGGCAA
GTCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAAGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TTCATGAGATAGGACTAGAGGGAAAACTATCAGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAACTATCAAGCCTAT
CTGAAAACTCAGGGAATTTACCAAACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGGTTGGCAGTTGGGATGTAGG
AGAAAATCTGTCCAGTTTACGCCGTAAGGCTGTAGTTTGGATAAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGGCTTTTGCTAGGACATCTGGATACGGACTTTGAGGAGATGAATGAGCTTTATTCTAGTCTAGGAATTATCCACCTT
TTTGCCTTGTCGGGCATGCAGGTAGGTTTTTTCATGGACGGGTTTAAGAAACTACTCTTGCGATTAGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACCTATCCCTTTTCTCTTATTTATGCAGGGCTGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTGGCTCAACATGGTGTTAAGGGCTTGGACAATTTTTCCCTGACGGTGCTTGTCCTCTTTATTATC
ATGTCCAACTTTTTCTTGACAGCAGGAGGAGTTTTGTCATGTGCTTATGCTTTTATCTTGACCATGACCAGCAAAGAAGG
AGAGGGTCTCAAGGCTGTGGTCAGAGAAAGTCTAGTCATTTCCTTGGGAATATTGCCCATTCTATCCTTCTATTTTGCAG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGCCTTTTCCTTTCTCTATCCAGTCATTCAGCTGAATTTTATTTTTGAATGGTTGGAGGAGATTATTCGCTTAGT
ATCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGCATGGCTTTTAGTCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAGGCTAGCAGTATTGAGCTTATTGATTATAGGTCTCTTTTTTCTGACCAAG
CATCCACTGGAAAATGAAATTACCATGCTGGATGTGGGGCAAGGGGAAAGTATTTTTCTACGTGATGTAACTGGTAAAAC
CATTCTCATAGATGTCGGTGGCAAGGCAGAATCTGACAAGAAAATCGAAAAATGGCAAGAAAAGACGACGACCAGCAATG
CTCAGCGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTGGCCAAGATTGATCAGCTGATTTTGACAAATACGGACAAG
GAACATGTTGGTGATTTGCTGGAGGTGACCAAGGCTTTCCATGTAGGGGAGATCTTAGTATCAAAAGGCAGTTTGAAACA
GAAGGAATTTGTTGCAGAACTACAGGCAACTCAAACCAAGGTGCGCAGTATAACAGCAGGAGAGACCTTGCAAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATGGAGATCATGAAGATTCCTTGGTTTTGTATGGAAAACTC
TTGGATAAAAACTTTCTTTTCACAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCATTATCCTGACCTAGA
GGTGGATGTTTTGAAAGCTAGCCAACATGGCTCTAAAAACTCATCAAGTTCAGCCTTTTTAGAACAGTTCAAACCAGAGA
TGACTCTCATTTCAGTTGGAAAGAATAATCGAACCAAACTACCCCATCAGGAAACCTTGACCCGACTGGAAACTATCAAT
AGCAAAGTATATCGAACTGACCAGCAAGGAGCTATACGCTTTAAAGGGTGGAATAGTTGGAAAATTGAAAGCGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-697)

• Domain of unknown function (DUF4131) (DUF4131) (30-177)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	93.691	99.866	0.936
comEC/celB	Streptococcus mitis SK321	93.432	100	0.934
comEC/celB	Streptococcus pneumoniae TIGR4	92.359	100	0.924
comEC/celB	Streptococcus pneumoniae D39	92.091	100	0.921
comEC/celB	Streptococcus pneumoniae Rx1	92.091	100	0.921
comEC/celB	Streptococcus pneumoniae R6	92.091	100	0.921
comEC	Lactococcus lactis subsp. cremoris KW2	44.624	99.732	0.445