Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACLV7Z_RS04380 Genome accession   NZ_OZ217343
Coordinates   892818..893555 (+) Length   245 a.a.
NCBI ID   WP_049512533.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 887818..898555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS04365 (SMIG22_08490) - 888089..890248 (+) 2160 WP_218774780.1 LicD family protein -
  ACLV7Z_RS04370 (SMIG22_08500) - 890307..891119 (+) 813 WP_218774781.1 LicD family protein -
  ACLV7Z_RS04375 (SMIG22_08510) - 891215..892693 (-) 1479 WP_218774782.1 oligosaccharide flippase family protein -
  ACLV7Z_RS04380 (SMIG22_08520) mecA 892818..893555 (+) 738 WP_049512533.1 adaptor protein MecA Regulator
  ACLV7Z_RS04385 (SMIG22_08530) - 893706..894992 (+) 1287 WP_218774783.1 homoserine dehydrogenase -
  ACLV7Z_RS04390 (SMIG22_08540) thrB 894994..895863 (+) 870 WP_218774784.1 homoserine kinase -
  ACLV7Z_RS04395 (SMIG22_08550) msrB 896099..897037 (+) 939 WP_218774785.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28474.22 Da        Isoelectric Point: 4.0199

>NTDB_id=1170204 ACLV7Z_RS04380 WP_049512533.1 892818..893555(+) (mecA) [Streptococcus mitis isolate S. mitis G22]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFS
KLADLVAFSKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVFN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1170204 ACLV7Z_RS04380 WP_049512533.1 892818..893555(+) (mecA) [Streptococcus mitis isolate S. mitis G22]
ATGAAAATGAAACAAATCAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGAGGCATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGTTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTAACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTACCAGATATGGAAGAATTGGCTCAAATGTCGCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGATAAAACCAAGGATGATATCGAAGCCATTCAATCTTTAGAGCAAGTCGAAGCCA
AGGAAGAAGAGCAGGAGCAGGCTGAACAAGAAGCTGAAAGCAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTTTCT
AAGTTAGCTGATTTGGTGGCTTTTTCAAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAATGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTTTTGGCTCGTATGCGCGAGT
TTGCGGACGATAGTGATATCAGTCGTTCAGTCTTGCAAGAGTATGGTCAAGTCTTGATGAATCACGATGCAGTGTTCAAT
CTGCAAAAGATTGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

97.959

100

0.98
  mecA Streptococcus pneumoniae D39

97.959

100

0.98
  mecA Streptococcus pneumoniae R6

97.959

100

0.98
  mecA Streptococcus pneumoniae TIGR4

97.551

100

0.976
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.486
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.482
  mecA Streptococcus mutans UA159

47.755

100

0.478

Multiple sequence alignment