Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACLV7Z_RS02690 Genome accession   NZ_OZ217343
Coordinates   511198..513177 (+) Length   659 a.a.
NCBI ID   WP_218774908.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 506198..518177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS02675 (SMIG22_05170) fmt 508205..509140 (+) 936 WP_218774910.1 methionyl-tRNA formyltransferase -
  ACLV7Z_RS02680 (SMIG22_05180) rsmB 509133..510446 (+) 1314 WP_218774909.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACLV7Z_RS02685 (SMIG22_05190) - 510461..511201 (+) 741 WP_000406247.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACLV7Z_RS02690 (SMIG22_05200) stkP 511198..513177 (+) 1980 WP_218774908.1 serine/threonine-protein kinase StkP Regulator
  ACLV7Z_RS02695 (SMIG22_05210) - 513292..514050 (+) 759 WP_218774907.1 threonine/serine exporter family protein -
  ACLV7Z_RS02700 (SMIG22_05220) - 514052..514501 (+) 450 WP_218774906.1 threonine/serine exporter family protein -
  ACLV7Z_RS02705 (SMIG22_05230) - 514662..514910 (+) 249 WP_218774935.1 hypothetical protein -
  ACLV7Z_RS02710 (SMIG22_05240) - 515041..516213 (+) 1173 WP_218774905.1 hydroxymethylglutaryl-CoA synthase -
  ACLV7Z_RS02715 (SMIG22_05250) - 516213..517487 (+) 1275 WP_218774904.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72460.10 Da        Isoelectric Point: 9.3249

>NTDB_id=1170194 ACLV7Z_RS02690 WP_218774908.1 511198..513177(+) (stkP) [Streptococcus mitis isolate S. mitis G22]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVSQSTLTSIPKVQAQTEHKPIK
KTSQAVTEETYQPQAPKKRRFKMRYLIFLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANFEIGEEKSE
ASERVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
MKQSLPEGTTYDLSKATQIVLTVAKKARTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
VPYDLSKSTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTKAPAGSAEGTVVEQSPRAGEKVDL
NKTRVKISIYKPKTNSATP

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=1170194 ACLV7Z_RS02690 WP_218774908.1 511198..513177(+) (stkP) [Streptococcus mitis isolate S. mitis G22]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGAACCAACTACCAGACAGACCCGATAG
CTGTGGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATTTAGACCATCCTCATATCGTTCGGATAACAGATATTGGC
GAGGAAGACGGTCAACAGTACCTAGCTATGGAGTATGTGGCTGGACTTGACCTCAAACGCTATATCAAGGAACACTATCC
TCTCTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGTTTGGCCCATACCAGAGGAATTGTCC
ATAGGGACTTGAAACCTCAAAACATTCTCTTGACACCAGATGGGACTGTCAAGGTTACAGACTTTGGGATTGCAGTAGCC
TTTGCTGAGACGAGTCTGACTCAGACTAACTCGATGCTGGGTTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTACAAAGTGATATCTATGCAATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTACGATG
GAGATAGTGCGGTGACCATCGCCCTCCAGCATTTCCAAAAACCACTGCCGTCCGTTATTGCTGAGAATCCATCTGTGCCC
CAGGCTTTGGAGAATGTTGTTATCAAGGCAACTGCTAAGAAATTGACAGATCGCTATAAATCAGTTGCTGAAATGTATGT
GGATTTGTCTAGTAGTTTGTCTTATAATCGTCGTAATGAACCAAAGCTGGTCTTTGACGATGCGACTAAGGCGGACACCA
AGACTCTACCAAAAGTATCCCAGAGCACCTTGACCTCGATTCCTAAGGTTCAAGCGCAGACAGAACACAAACCAATCAAA
AAAACAAGTCAGGCTGTGACAGAGGAAACCTACCAACCACAAGCACCGAAAAAACGTAGATTTAAGATGCGTTACCTGAT
TTTTTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTGATTTGGATACTATCCAGAACTCCTGCAACTATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCGGAAGCCAAGGAAACCCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAGTCAGAG
GCTAGTGAAAGGGTGGAAGAGGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCTTTCCAAATTAGTAATTATGTTGGTCGGAAATCCTCTGATGTCATTGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
ATGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TAGGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTCATCTCGGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCAGGT
GTTCCTTATGATTTAAGTAAATCTACTCAAATCGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGCTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCCAATATAGAAGTTGTAG
AAGTGACGAAAGCGCCTGCAGGTAGTGCTGAAGGTACAGTCGTTGAACAGAGTCCTAGAGCAGGTGAAAAGGTAGACCTC
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAAATTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(582-651)

PASTA domain (PASTA)

(513-577)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

95.903

100

0.959
  stkP Streptococcus pneumoniae D39

95.448

100

0.954
  stkP Streptococcus pneumoniae R6

95.448

100

0.954
  stkP Streptococcus pneumoniae Rx1

95.296

100

0.953
  pknB Streptococcus mutans UA159

53.846

88.771

0.478
  stkP/pknB Streptococcus salivarius strain HSISS4

51.807

88.164

0.457

Multiple sequence alignment