Detailed information NTG1170193

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: ACLV7Z_RS02315
• Genome accession: NZ_OZ217343
• Coordinates: 428508..429167 (-)
• Length: 219 a.a.
• NCBI ID: WP_071478877.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis G22
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 423508..434167

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Z_RS02285 (SMIG22_04450)	-	423688..424287 (+)	600	WP_218774149.1	phosphoribosylanthranilate isomerase	-
ACLV7Z_RS02290 (SMIG22_04460)	trpB	424265..425488 (+)	1224	WP_218774148.1	tryptophan synthase subunit beta	-
ACLV7Z_RS02295 (SMIG22_04470)	trpA	425481..426257 (+)	777	WP_218774147.1	tryptophan synthase subunit alpha	-
ACLV7Z_RS02300	-	426229..426330 (-)	102	Protein_399	prepilin peptidase	-
ACLV7Z_RS02305 (SMIG22_04480)	-	426559..427290 (+)	732	WP_071478875.1	hypothetical protein	-
ACLV7Z_RS02310 (SMIG22_04490)	-	427305..428456 (+)	1152	WP_130886591.1	XRE family transcriptional regulator	-
ACLV7Z_RS02315 (SMIG22_04500)	cclA/cilC	428508..429167 (-)	660	WP_071478877.1	prepilin peptidase	Machinery gene
ACLV7Z_RS02320 (SMIG22_04510)	-	429237..429692 (+)	456	WP_218774146.1	GNAT family N-acetyltransferase	-
ACLV7Z_RS02325 (SMIG22_04520)	-	429815..430993 (-)	1179	WP_218774145.1	ROK family transcriptional regulator	-
ACLV7Z_RS02330 (SMIG22_04530)	-	431399..432295 (+)	897	WP_164226077.1	WecB/TagA/CpsF family glycosyltransferase	-
ACLV7Z_RS02335 (SMIG22_04540)	-	432310..432627 (+)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
ACLV7Z_RS02340 (SMIG22_04550)	-	432644..432961 (+)	318	WP_050239156.1	PTS lactose/cellobiose transporter subunit IIA	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24951.23 Da
• Isoelectric Point: 7.5762

>NTDB_id=1170193 ACLV7Z_RS02315 WP_071478877.1 428508..429167(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis G22]
MIDFYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCQTRLRPLDLIPILSQVLNRFRCRYCKAPYPIWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIACSGWNLVMVFFLVLGIVAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASTMGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=1170193 ACLV7Z_RS02315 WP_071478877.1 428508..429167(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis G22]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTTATTGACCGTTTTCCTGAGCA
ATCCATTATCCAACCTGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCTATTCTCTCGC
AGGTGCTCAATCGCTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCTATTTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCCTGCTCTGGCTGGA
ATCTAGTCATGGTCTTCTTCCTTGTCCTTGGAATTGTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTTCTC
TTTCTAGCTTCTTGTGCTCTCGTCTTTAGTGTGACCGAATTACTCATCTTGATTCAGTTTGCTTCTACGATGGGAATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTCGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	94.064	100	0.941
cclA/cilC	Streptococcus pneumoniae D39	94.064	100	0.941
cclA/cilC	Streptococcus pneumoniae R6	94.064	100	0.941
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus pneumoniae TIGR4	89.954	100	0.9
cclA/cilC	Streptococcus mitis NCTC 12261	88.128	100	0.881