Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACLV65_RS02605 Genome accession   NZ_OZ217342
Coordinates   493468..495369 (+) Length   633 a.a.
NCBI ID   WP_218757412.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 488468..500369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS02590 (SMIB22_05020) fmt 490475..491410 (+) 936 WP_411864443.1 methionyl-tRNA formyltransferase -
  ACLV65_RS02595 (SMIB22_05030) rsmB 491403..492716 (+) 1314 WP_411864444.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACLV65_RS02600 (SMIB22_05040) - 492731..493471 (+) 741 WP_000406237.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACLV65_RS02605 (SMIB22_05050) stkP 493468..495369 (+) 1902 WP_218757412.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACLV65_RS02610 (SMIB22_05060) - 495458..496216 (+) 759 WP_218757413.1 threonine/serine exporter family protein -
  ACLV65_RS02615 (SMIB22_05070) - 496218..496667 (+) 450 WP_057487161.1 threonine/serine exporter family protein -
  ACLV65_RS02620 (SMIB22_05080) - 496828..497076 (+) 249 WP_218757443.1 hypothetical protein -
  ACLV65_RS02625 (SMIB22_05090) - 497207..498379 (+) 1173 WP_411864445.1 hydroxymethylglutaryl-CoA synthase -
  ACLV65_RS02630 (SMIB22_05100) - 498379..499650 (+) 1272 WP_411864446.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69184.71 Da        Isoelectric Point: 9.2741

>NTDB_id=1170111 ACLV65_RS02605 WP_218757412.1 493468..495369(+) (stkP) [Streptococcus mitis isolate S. mitis B22]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIDENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVSQSTLTSIPKVQAQTEHKPIK
KTSQAVTEETYQPQAPKKRRFKMRYLIFLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSTDVIAELKQKKVPENLIKIEEEESSESEAGTV
LRQSPVAGTTYDLSKASTITLTVAKKVTSVAMPSYIGSSLEFTKNNLVQIVGIKEANIEVVEVSTAPDGTAEGTVVEQSP
KAGEKVDLTKTRVKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRGNAPAPTQSSSEVNHENSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=1170111 ACLV65_RS02605 WP_218757412.1 493468..495369(+) (stkP) [Streptococcus mitis isolate S. mitis B22]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAAATTGGTCGAGGAGGCATGGCGGATGTCTA
CTTGGCCAAAGATTTGATTCTGGACGGGGAAGAAGTGGCAGTGAAGGTTCTGAGAACCAACTACCAGACAGACCCGATAG
CTGTGGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATTTAGACCATCCTCATATCGTTCGGATAACAGATATTGGC
GAGGAAGACGGTCAACAGTACCTAGCTATGGAGTATGTGGCTGGACTTGACCTTAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATCCTCCTAGCCATGCGTTTGGCCCATACCAGAGGAATTGTTC
ACCGGGACTTGAAACCTCAAAATATCCTCTTGACACCAGATGGGACTGTCAAGGTTACAGACTTTGGGATTGCAGTAGCC
TTTGCTGAGACGAGTCTGACTCAGACTAACTCGATGCTGGGTTCGGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
AAAGGCGACTGTACAAAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTATGACG
GGGATAGTGCGGTGACCATCGCCCTCCAGCATTTCCAGAAACCACTGCCGTCAGTTATTGATGAGAATCCATCTGTGCCC
CAGGCTTTGGAGAATGTTGTTATCAAGGCAACTGCTAAGAAATTGACAGATCGCTATAAATCAGTTGCTGAAATGTATGT
GGATTTGTCTAGTAGTTTGTCTTATAATCGTCGTAATGAACCAAAGCTGGTCTTTGACGATGCGACTAAGGCGGACACCA
AGACTCTACCAAAGGTATCCCAGAGTACCTTGACTTCGATTCCTAAGGTTCAAGCGCAGACAGAACACAAACCAATCAAA
AAAACAAGTCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACGTAGATTTAAGATGCGTTACCTGAT
TTTTTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTGATTTGGATACTATCCAGAACTCCTGCAACTATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCGGAAGCCAAGGAAACGCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAGTCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCCGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCCTTCCAAATTAGTAATTATGTCGGTCGGAAATCGACAGATGTTATCGCAG
AACTCAAGCAGAAGAAGGTTCCTGAAAATCTCATCAAGATTGAAGAAGAGGAATCAAGTGAGAGTGAAGCAGGAACCGTT
CTCAGACAGAGTCCAGTTGCCGGAACAACCTATGATTTGAGCAAGGCCTCAACGATTACCTTAACCGTTGCTAAGAAAGT
AACTAGTGTTGCTATGCCAAGTTATATAGGATCTAGTCTCGAATTTACTAAAAACAATCTCGTTCAAATTGTTGGGATTA
AGGAAGCCAATATTGAAGTTGTAGAAGTGTCGACAGCTCCTGATGGAACTGCTGAGGGTACAGTCGTTGAACAGAGTCCA
AAAGCGGGTGAAAAGGTTGATTTGACTAAGACGCGTGTCAAGATTTCAATCTACAAACCAAAAACACCGCCGTCAACGTC
ATCATCAGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACGACACCAAGTCAGGGGAACCAACAAGGAAATCAACGAG
GGAATGCACCTGCTCCTACTCAATCAAGTAGTGAAGTGAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

84.812

92.575

0.785
  stkP Streptococcus pneumoniae D39

84.471

92.575

0.782
  stkP Streptococcus pneumoniae R6

84.471

92.575

0.782
  stkP Streptococcus pneumoniae Rx1

84.3

92.575

0.78
  stkP/pknB Streptococcus salivarius strain HSISS4

53.547

93.523

0.501
  pknB Streptococcus mutans UA159

54.939

91.153

0.501

Multiple sequence alignment