Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACLV7Q_RS05310 Genome accession   NZ_OZ217341
Coordinates   1069727..1070464 (-) Length   245 a.a.
NCBI ID   WP_081529705.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1064727..1075464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS05290 (SMIC22_10350) msrB 1065959..1066897 (-) 939 WP_218758041.1 peptide-methionine (R)-S-oxide reductase MsrB -
  ACLV7Q_RS05295 - 1067256..1067327 (+) 72 Protein_996 transposase -
  ACLV7Q_RS05300 (SMIC22_10360) thrB 1067418..1068287 (-) 870 WP_050242142.1 homoserine kinase -
  ACLV7Q_RS05305 (SMIC22_10370) - 1068289..1069575 (-) 1287 WP_218758040.1 homoserine dehydrogenase -
  ACLV7Q_RS05310 (SMIC22_10380) mecA 1069727..1070464 (-) 738 WP_081529705.1 adaptor protein MecA Regulator
  ACLV7Q_RS05315 (SMIC22_10390) - 1070781..1071815 (-) 1035 WP_218758039.1 prephenate dehydratase -
  ACLV7Q_RS05320 (SMIC22_10400) - 1071808..1073277 (-) 1470 WP_218758038.1 O-antigen polysaccharide polymerase Wzy family protein -
  ACLV7Q_RS05325 (SMIC22_10410) - 1073293..1074279 (-) 987 WP_218758037.1 glycosyltransferase family 2 protein -
  ACLV7Q_RS05330 (SMIC22_10420) - 1074281..1075384 (-) 1104 WP_172923862.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28421.16 Da        Isoelectric Point: 3.9841

>NTDB_id=1170042 ACLV7Q_RS05310 WP_081529705.1 1069727..1070464(-) (mecA) [Streptococcus mitis isolate S. mitis C22]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQDQQEAEGKKEPYIYYILSFA
KLADLVAFAQTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1170042 ACLV7Q_RS05310 WP_081529705.1 1069727..1070464(-) (mecA) [Streptococcus mitis isolate S. mitis C22]
ATGAAAATGAAACAAATTAGTGATACTACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGCATGGAGAT
TGCTGACTTTCTTGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGTTAGAGATGCCTGATAGCT
TTCTAGATACAGGTATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTAACCAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGATTTATCGGATTTACCAGATATGGAAGAATTGGCTCAAATGTCGCCAGATGAGTTTAT
TAAAACTTTAGAAAAAAGCATCGCGGACAAAACCAAAGATGATATCGAAGCCATTCAATCTCTAGAGCAAGTCGAAGCCA
AGGAAGAAGAGCAGGAGCAGGATCAACAAGAAGCTGAAGGCAAGAAAGAGCCCTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTGGCTTTTGCCCAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTCTTGGCCCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGTTCAGTTTTGCAAGAGTATGGCCAAGTCTTGATGAATCACGATGCTGTGCTCAAT
CTGCAAAAAATCGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

97.551

100

0.976
  mecA Streptococcus pneumoniae D39

97.551

100

0.976
  mecA Streptococcus pneumoniae R6

97.551

100

0.976
  mecA Streptococcus pneumoniae TIGR4

97.143

100

0.971
  mecA Streptococcus thermophilus LMD-9

46.988

100

0.478
  mecA Streptococcus mutans UA159

47.347

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.586

100

0.473

Multiple sequence alignment