Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACLV7Q_RS02505 Genome accession   NZ_OZ217341
Coordinates   470723..472624 (+) Length   633 a.a.
NCBI ID   WP_218757412.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 465723..477624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS02490 (SMIC22_04790) fmt 467730..468665 (+) 936 WP_218757410.1 methionyl-tRNA formyltransferase -
  ACLV7Q_RS02495 (SMIC22_04800) rsmB 468658..469971 (+) 1314 WP_218757411.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACLV7Q_RS02500 (SMIC22_04810) - 469986..470726 (+) 741 WP_050234902.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACLV7Q_RS02505 (SMIC22_04820) stkP 470723..472624 (+) 1902 WP_218757412.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACLV7Q_RS02510 (SMIC22_04830) - 472713..473471 (+) 759 WP_218757413.1 threonine/serine exporter family protein -
  ACLV7Q_RS02515 (SMIC22_04840) - 473473..473922 (+) 450 WP_057487161.1 threonine/serine exporter family protein -
  ACLV7Q_RS02520 (SMIC22_04850) - 474083..474331 (+) 249 WP_218757443.1 hypothetical protein -
  ACLV7Q_RS02525 (SMIC22_04860) - 474462..475634 (+) 1173 WP_218757444.1 hydroxymethylglutaryl-CoA synthase -
  ACLV7Q_RS02530 (SMIC22_04870) - 475634..476908 (+) 1275 WP_218757414.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69184.71 Da        Isoelectric Point: 9.2741

>NTDB_id=1170029 ACLV7Q_RS02505 WP_218757412.1 470723..472624(+) (stkP) [Streptococcus mitis isolate S. mitis C22]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIDENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVSQSTLTSIPKVQAQTEHKPIK
KTSQAVTEETYQPQAPKKRRFKMRYLIFLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSTDVIAELKQKKVPENLIKIEEEESSESEAGTV
LRQSPVAGTTYDLSKASTITLTVAKKVTSVAMPSYIGSSLEFTKNNLVQIVGIKEANIEVVEVSTAPDGTAEGTVVEQSP
KAGEKVDLTKTRVKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRGNAPAPTQSSSEVNHENSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=1170029 ACLV7Q_RS02505 WP_218757412.1 470723..472624(+) (stkP) [Streptococcus mitis isolate S. mitis C22]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGAACCAACTACCAGACAGACCCGATAG
CTGTGGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATTTAGACCATCCTCATATCGTTCGGATAACAGATATTGGC
GAGGAAGACGGTCAACAGTACCTAGCTATGGAGTATGTGGCTGGACTTGACCTCAAACGCTATATCAAGGAACACTATCC
TCTCTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGTTTGGCCCATACCAGAGGAATTGTTC
ACCGGGACTTGAAACCTCAAAACATCCTCTTGACACCAGATGGGACTGTCAAGGTTACAGACTTTGGGATTGCAGTAGCC
TTTGCTGAGACGAGTCTGACTCAGACTAACTCGATGCTGGGTTCGGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
AAAGGCGACTGTACAAAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTATGACG
GGGATAGTGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCACTGCCGTCAGTTATTGATGAGAATCCATCTGTGCCC
CAGGCTTTGGAGAATGTTGTTATCAAGGCAACTGCTAAGAAATTGACAGATCGCTATAAATCAGTTGCTGAAATGTATGT
GGATTTGTCTAGTAGTTTGTCTTATAATCGTCGTAATGAACCAAAGCTGGTCTTTGACGATGCGACTAAGGCGGACACCA
AGACTCTACCAAAGGTATCCCAGAGTACCTTGACTTCGATTCCTAAGGTTCAAGCGCAGACAGAACACAAACCAATCAAA
AAAACAAGTCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACGTAGATTTAAGATGCGTTACCTGAT
TTTTTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTGATTTGGATACTATCCAGAACTCCTGCAACTATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCGGAAGCCAAGGAAACGCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAGTCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCCGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCCTTCCAAATTAGTAATTATGTCGGTCGGAAATCGACAGATGTTATCGCAG
AACTCAAGCAGAAGAAGGTTCCTGAAAATCTCATCAAGATTGAAGAAGAGGAATCAAGTGAGAGTGAAGCAGGAACCGTT
CTCAGACAGAGTCCAGTTGCCGGAACAACCTATGATTTGAGCAAGGCCTCAACGATTACCTTAACCGTTGCTAAGAAAGT
AACTAGTGTTGCTATGCCAAGTTATATAGGATCTAGTCTCGAATTTACTAAAAACAATCTCGTTCAAATTGTTGGGATTA
AGGAAGCCAATATTGAAGTTGTAGAAGTGTCGACAGCTCCTGATGGAACTGCTGAGGGTACAGTCGTTGAACAGAGTCCA
AAAGCGGGTGAAAAGGTTGATTTGACTAAGACGCGTGTCAAGATTTCAATCTACAAACCAAAAACACCGCCGTCAACGTC
ATCATCAGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACGACACCAAGTCAGGGGAACCAACAAGGAAATCAACGAG
GGAATGCACCTGCTCCTACTCAATCAAGTAGTGAAGTGAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

84.812

92.575

0.785
  stkP Streptococcus pneumoniae D39

84.471

92.575

0.782
  stkP Streptococcus pneumoniae R6

84.471

92.575

0.782
  stkP Streptococcus pneumoniae Rx1

84.3

92.575

0.78
  stkP/pknB Streptococcus salivarius strain HSISS4

53.547

93.523

0.501
  pknB Streptococcus mutans UA159

54.939

91.153

0.501

Multiple sequence alignment