Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACLV7Q_RS02260 Genome accession   NZ_OZ217341
Coordinates   429823..430482 (-) Length   219 a.a.
NCBI ID   WP_218757387.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 424823..435482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS02230 (SMIC22_04280) - 425003..425602 (+) 600 WP_218757382.1 phosphoribosylanthranilate isomerase -
  ACLV7Q_RS02235 (SMIC22_04290) trpB 425580..426803 (+) 1224 WP_218757383.1 tryptophan synthase subunit beta -
  ACLV7Q_RS02240 (SMIC22_04300) trpA 426796..427572 (+) 777 WP_218757384.1 tryptophan synthase subunit alpha -
  ACLV7Q_RS02245 - 427544..427645 (-) 102 Protein_388 prepilin peptidase -
  ACLV7Q_RS02250 (SMIC22_04310) - 427874..428605 (+) 732 WP_218757385.1 hypothetical protein -
  ACLV7Q_RS02255 (SMIC22_04320) - 428620..429771 (+) 1152 WP_218757386.1 ImmA/IrrE family metallo-endopeptidase -
  ACLV7Q_RS02260 (SMIC22_04330) cclA/cilC 429823..430482 (-) 660 WP_218757387.1 prepilin peptidase Machinery gene
  ACLV7Q_RS02265 (SMIC22_04340) - 430552..431007 (+) 456 WP_218757388.1 GNAT family N-acetyltransferase -
  ACLV7Q_RS02270 (SMIC22_04350) - 431189..432190 (+) 1002 WP_218757389.1 LacI family DNA-binding transcriptional regulator -
  ACLV7Q_RS02275 (SMIC22_04360) - 432343..433260 (+) 918 WP_001084979.1 ABC transporter permease -
  ACLV7Q_RS02280 (SMIC22_04370) - 433271..434161 (+) 891 WP_050306002.1 carbohydrate ABC transporter permease -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24875.02 Da        Isoelectric Point: 6.9204

>NTDB_id=1170028 ACLV7Q_RS02260 WP_218757387.1 429823..430482(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis C22]
MIDFYFFLVGSILASFLGLLIDRFPEQSIIQPASHCDSCQTPLRPLDLIPIFSQVFHLFRCRYCKAPYPVWYALFELGLG
LLFLSWSWGFLSLGQVVLITAGLTLGIYDFRHQEYPLLVWMTFHLILMACSGWNLVMVFFLVLGMLAHFIDIRMGAGDFL
FLASCALVFSATELLILIQFASETGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1170028 ACLV7Q_RS02260 WP_218757387.1 429823..430482(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis C22]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGCTCATTGACCGTTTTCCTGAGCA
ATCCATTATCCAACCTGCTAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCTATTTTCTCGC
AGGTCTTTCATCTCTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCTGTCTGGTATGCCCTTTTTGAACTAGGCTTAGGG
CTCCTCTTTCTATCTTGGTCTTGGGGCTTTCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTCATGGCCTGTTCTGGCTGGA
ATCTAGTCATGGTCTTCTTCCTTGTCCTTGGAATGTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTTCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGCAACCGAGTTACTCATCTTGATTCAGTTTGCTTCTGAGACGGGCATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae TIGR4

89.498

100

0.895
  cclA/cilC Streptococcus pneumoniae Rx1

89.498

100

0.895
  cclA/cilC Streptococcus pneumoniae D39

89.498

100

0.895
  cclA/cilC Streptococcus pneumoniae R6

89.498

100

0.895
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment