Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   ACLV7Q_RS00115 Genome accession   NZ_OZ217341
Coordinates   20981..21217 (+) Length   78 a.a.
NCBI ID   WP_049524667.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 15981..26217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS00105 - 20185..20481 (-) 297 Protein_14 transposase family protein -
  ACLV7Q_RS00110 - 20611..20839 (-) 229 Protein_15 transposase -
  ACLV7Q_RS00115 (SMIC22_00180) comW 20981..21217 (+) 237 WP_049524667.1 sigma(X)-activator ComW Regulator
  ACLV7Q_RS00120 (SMIC22_00190) - 21448..22734 (+) 1287 WP_001832534.1 adenylosuccinate synthase -
  ACLV7Q_RS00125 (SMIC22_00210) tadA 22934..23401 (+) 468 WP_001110110.1 tRNA adenosine(34) deaminase TadA -
  ACLV7Q_RS00135 (SMIC22_00230) - 23588..24031 (+) 444 WP_000701987.1 dUTP diphosphatase -
  ACLV7Q_RS00140 (SMIC22_00240) - 23982..24548 (+) 567 WP_218757492.1 histidine phosphatase family protein -
  ACLV7Q_RS00145 (SMIC22_00250) radA 24562..25923 (+) 1362 WP_411866013.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9805.21 Da        Isoelectric Point: 4.7163

>NTDB_id=1169998 ACLV7Q_RS00115 WP_049524667.1 20981..21217(+) (comW) [Streptococcus mitis isolate S. mitis C22]
MLQSIYDQMTDFYDSIEEEYATFFDNSWEWEDFHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLIMKQGFVAC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1169998 ACLV7Q_RS00115 WP_049524667.1 20981..21217(+) (comW) [Streptococcus mitis isolate S. mitis C22]
ATGCTACAAAGTATTTATGATCAGATGACTGATTTCTATGACAGTATCGAAGAAGAGTATGCTACTTTCTTTGATAATAG
TTGGGAATGGGAAGATTTTCATTTTAAATTTTTGATTTATTATTTAGTTAGATATGGCATTGGGTGTCGTAGGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGATAATGAAACAAGGTTTTGTTGCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus mitis SK321

79.487

100

0.795

  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769

  comW Streptococcus pneumoniae Rx1

74.359

100

0.744

  comW Streptococcus pneumoniae D39

74.359

100

0.744

  comW Streptococcus pneumoniae R6

74.359

100

0.744

  comW Streptococcus pneumoniae TIGR4

74.359

100

0.744


Multiple sequence alignment