Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACLV7H_RS06635 Genome accession   NZ_OZ217340
Coordinates   1254509..1255249 (-) Length   246 a.a.
NCBI ID   WP_000782704.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1249509..1260249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS06620 (SORA22_13330) msrB 1251166..1252104 (-) 939 WP_411866718.1 peptide-methionine (R)-S-oxide reductase MsrB -
  ACLV7H_RS06625 (SORA22_13340) thrB 1252204..1253073 (-) 870 WP_045590933.1 homoserine kinase -
  ACLV7H_RS06630 (SORA22_13350) - 1253075..1254361 (-) 1287 WP_045590932.1 homoserine dehydrogenase -
  ACLV7H_RS06635 (SORA22_13360) mecA 1254509..1255249 (-) 741 WP_000782704.1 adaptor protein MecA Regulator
  ACLV7H_RS06640 (SORA22_13370) - 1255372..1256850 (+) 1479 WP_045590930.1 oligosaccharide flippase family protein -
  ACLV7H_RS06645 (SORA22_13380) - 1256896..1259424 (-) 2529 WP_411866719.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28497.30 Da        Isoelectric Point: 4.1097

>NTDB_id=1169967 ACLV7H_RS06635 WP_000782704.1 1254509..1255249(-) (mecA) [Streptococcus oralis isolate S. oralis A22]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=1169967 ACLV7H_RS06635 WP_000782704.1 1254509..1255249(-) (mecA) [Streptococcus oralis isolate S. oralis A22]
ATGAAGATGAAACAAATCAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCGATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTCGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGATAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATATACTATATCCTGCGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTATCAGATGGAAACCTCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTAGAAAATCATCCAAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAGT
TCGCAGACGACAGTGATATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.984

99.187

0.902
  mecA Streptococcus pneumoniae D39

90.984

99.187

0.902
  mecA Streptococcus pneumoniae R6

90.984

99.187

0.902
  mecA Streptococcus pneumoniae TIGR4

90.574

99.187

0.898
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.48

Multiple sequence alignment