Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACLV7H_RS00455 Genome accession   NZ_OZ217340
Coordinates   67878..69227 (+) Length   449 a.a.
NCBI ID   WP_411866067.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 62878..74227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS00425 (SORA22_00820) - 63706..63942 (+) 237 WP_411866063.1 acyl carrier protein -
  ACLV7H_RS00430 (SORA22_00830) - 64262..64456 (+) 195 WP_411866064.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACLV7H_RS00435 (SORA22_00850) - 64687..64860 (+) 174 WP_001056923.1 hypothetical protein -
  ACLV7H_RS00440 - 64861..65088 (+) 228 WP_080933732.1 bacteriocin immunity protein -
  ACLV7H_RS00445 (SORA22_00860) - 65160..65348 (+) 189 WP_411866065.1 hypothetical protein -
  ACLV7H_RS00450 (SORA22_00880) comA 65712..67865 (+) 2154 WP_411866066.1 peptide cleavage/export ABC transporter ComA Regulator
  ACLV7H_RS00455 (SORA22_00890) comB 67878..69227 (+) 1350 WP_411866067.1 competence pheromone export protein ComB Regulator
  ACLV7H_RS00460 (SORA22_00900) purC 69395..70102 (+) 708 WP_045593802.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  ACLV7H_RS00465 (SORA22_00910) - 70305..74030 (+) 3726 WP_411866068.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49872.84 Da        Isoelectric Point: 5.4072

>NTDB_id=1169925 ACLV7H_RS00455 WP_411866067.1 67878..69227(+) (comB) [Streptococcus oralis isolate S. oralis A22]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAFFAEKEISLSTRATVEPSRIIANIQSTSNQRIVVNYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKNQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ANISSQNAAASQSKAEIGNLINQTQDKIRDYKTAKSAIETGNQLDSQNAAYSFYQTYKNQAGDESQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVIH
LNPETSDSTMVAEGALIAQLYPALEREGKTKLTAYLSSKDVARLQVGDSVRFTTSKDANKELVLVSAITNIDATATKTEK
GNFFKIEAETSLTPEQAESLRYGSEGRLTLITGKKSYLRYYWDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1169925 ACLV7H_RS00455 WP_411866067.1 67878..69227(+) (comB) [Streptococcus oralis isolate S. oralis A22]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCGCTTCTGCTCGTGTTTCTGTTAGGATTTGCATTTTTTGCAGAGAAGGAGATTAGTTTGTCTACTAGAGCAACTGTCG
AACCTAGTCGGATCATTGCTAATATCCAGTCGACTAGCAATCAACGCATTGTGGTCAACTATCTGGAAGAAAACAAATTG
GTCAAGCAAGGGGACCTACTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAAGCATACGCCAGTCAATTGGA
GATGCTAAAGAATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATACCAGGAGATGTTTCGAGACTACCTCAGCCAAGCTAGTAGTCTTAGGAGCAATGTTTCGCAGCAAAAT
GCTAACATCTCCTCGCAGAATGCAGCAGCAAGTCAGAGTAAGGCCGAGATTGGCAATCTTATCAACCAAACACAGGATAA
AATCCGAGATTACAAAACAGCTAAGTCAGCGATTGAAACAGGAAATCAACTGGATAGTCAAAATGCAGCCTACTCTTTTT
ATCAGACCTATAAAAACCAAGCTGGAGATGAATCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATCGCT
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGATCTGGAGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTTGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGTCAGGAATTAACCCTTTTGGATCAGAAAATTTTGG
AGGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAAGGGAAAATTACAGCAAGCGAGGATGGGGTGATTCAC
CTTAATCCTGAAACCAGTGATTCTACCATGGTTGCAGAGGGGGCCTTGATCGCCCAACTCTACCCAGCCTTGGAACGAGA
AGGCAAAACTAAACTCACGGCTTATCTCAGTTCAAAAGATGTTGCAAGGCTCCAGGTCGGTGATTCTGTTCGTTTCACTA
CAAGCAAAGATGCCAATAAAGAGCTCGTTCTTGTTTCTGCCATTACGAATATTGACGCGACAGCTACCAAGACAGAAAAG
GGAAATTTCTTTAAAATAGAGGCGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGACG
TTTGACACTAATCACAGGGAAGAAAAGCTATTTGCGCTATTATTGGGATCAATTTTTGAACAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae R6

79.51

100

0.795
  comB Streptococcus pneumoniae Rx1

79.51

100

0.795
  comB Streptococcus pneumoniae D39

79.51

100

0.795
  comB Streptococcus pneumoniae TIGR4

79.51

100

0.795
  comB Streptococcus mitis SK321

79.287

100

0.793
  comB Streptococcus mitis NCTC 12261

78.174

100

0.782
  comB Streptococcus gordonii str. Challis substr. CH1

53.556

100

0.537

Multiple sequence alignment