Detailed information NTG1169498

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ACNUD9_RS13020
• Genome accession: NZ_OZ197096
• Coordinates: 2677915..2679213 (-)
• Length: 432 a.a.
• NCBI ID: WP_002406460.1
• Uniprot ID: A0A855UIE9
• Organism: Enterococcus faecalis isolate 23S00039-2
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2672915..2684213

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD9_RS12985	-	2673157..2673888 (+)	732	WP_002365323.1	GntR family transcriptional regulator	-
ACNUD9_RS12990	-	2673903..2674313 (+)	411	WP_002359084.1	PTS sugar transporter subunit IIA	-
ACNUD9_RS12995	-	2674325..2675068 (+)	744	WP_002387355.1	BtpA/SgcQ family protein	-
ACNUD9_RS13000	-	2675071..2675544 (+)	474	WP_002359087.1	PTS sugar transporter subunit IIB	-
ACNUD9_RS13005	-	2675566..2676336 (+)	771	WP_416692751.1	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	-
ACNUD9_RS13010	-	2676320..2677144 (+)	825	WP_002385250.1	PTS system mannose/fructose/sorbose family transporter subunit IID	-
ACNUD9_RS13015	ytpR	2677248..2677868 (+)	621	WP_002361057.1	YtpR family tRNA-binding protein	-
ACNUD9_RS13020	htrA	2677915..2679213 (-)	1299	WP_002406460.1	S1C family serine protease	Regulator
ACNUD9_RS13025	rlmH	2679614..2680093 (+)	480	WP_002355021.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 44861.98 Da
• Isoelectric Point: 4.9968

>NTDB_id=1169498 ACNUD9_RS13020 WP_002406460.1 2677915..2679213(-) (htrA) [Enterococcus faecalis isolate 23S00039-2]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPTSVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide

• Length: 1299 bp

>NTDB_id=1169498 ACNUD9_RS13020 WP_002406460.1 2677915..2679213(-) (htrA) [Enterococcus faecalis isolate 23S00039-2]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACATCCACTAATCACGGCGACACAAAAGTCAGCAATGTAAGTTACAATGTGTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGAAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCTATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAACTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACTATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (132-277)

• Peptidase family M50 (Peptidase_M50) (9-416)

• PDZ domain (PDZ_2) (319-416)

3D structure

• AlphaFold DB: A0A855UIE9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	53.171	94.907	0.505
htrA	Streptococcus mutans UA159	58.63	84.491	0.495
htrA	Streptococcus mitis NCTC 12261	55.135	85.648	0.472
htrA	Streptococcus pneumoniae TIGR4	55.807	81.713	0.456
htrA	Streptococcus pneumoniae Rx1	55.807	81.713	0.456
htrA	Streptococcus pneumoniae D39	55.807	81.713	0.456
htrA	Streptococcus pneumoniae R6	55.807	81.713	0.456