Detailed information NTG0116368

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: AF91_RS11395
• Genome accession: NZ_CP007122
• Coordinates: 2311847..2314039 (-)
• Length: 730 a.a.
• NCBI ID: WP_025376283.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei N1115
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2306847..2319039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AF91_RS11365 (AF91_11765)	-	2307017..2307301 (-)	285	WP_003599758.1	bacteriocin immunity protein	-
AF91_RS11370 (AF91_11770)	-	2307494..2307788 (-)	295	Protein_2220	bacteriocin immunity protein	-
AF91_RS11375 (AF91_11775)	-	2307889..2309244 (-)	1356	WP_003567335.1	threonine/serine exporter ThrE family protein	-
AF91_RS11380 (AF91_11780)	-	2309550..2309861 (-)	312	WP_003580849.1	hypothetical protein	-
AF91_RS16220 (AF91_11785)	-	2309934..2310283 (-)	350	Protein_2223	hypothetical protein	-
AF91_RS11390 (AF91_11790)	-	2310457..2311836 (-)	1380	WP_016366046.1	bacteriocin secretion accessory protein	-
AF91_RS11395 (AF91_11795)	comA	2311847..2314039 (-)	2193	WP_025376283.1	peptide cleavage/export ABC transporter	Regulator
AF91_RS11400 (AF91_11800)	-	2314296..2315216 (+)	921	WP_003574021.1	IS30 family transposase	-
AF91_RS11405 (AF91_11805)	-	2315560..2315697 (-)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
AF91_RS17720 (AF91_11810)	-	2316066..2316578 (+)	513	Protein_2228	histidine kinase	-
AF91_RS11415 (AF91_11815)	-	2316660..2316947 (+)	288	WP_003688751.1	transposase	-
AF91_RS11420 (AF91_11820)	-	2316971..2317849 (+)	879	WP_003688752.1	IS3 family transposase	-
AF91_RS11425 (AF91_11825)	-	2317898..2318506 (+)	609	Protein_2231	GHKL domain-containing protein	-
AF91_RS11430 (AF91_11830)	-	2318511..2318798 (+)	288	Protein_2232	DNA-binding response regulator	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81346.61 Da
• Isoelectric Point: 7.0227

>NTDB_id=116368 AF91_RS11395 WP_025376283.1 2311847..2314039(-) (comA) [Lacticaseibacillus paracasei N1115]
MIKYNIKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQLRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVTEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=116368 AF91_RS11395 WP_025376283.1 2311847..2314039(-) (comA) [Lacticaseibacillus paracasei N1115]
ATGATCAAATACAACATAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAATTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGCTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCACCAGAACCGCAATATCAACTACGCAAAGAGGAT
AAAGGCAGTCTTTTTGCGTTTGTGCCGATGCTGGCACGGCAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGCCTCATCCTCGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCTATTATCGAAGACTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCTGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCCATC
AGTGATGTTGATCTAACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCTGATATTGAAGCTGCCTGTTCAGTGACGGAAATTGCTG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGGAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTAACCATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.635	98.356	0.577
comA	Streptococcus pneumoniae Rx1	58.078	98.356	0.571
comA	Streptococcus pneumoniae D39	58.078	98.356	0.571
comA	Streptococcus pneumoniae R6	58.078	98.356	0.571
comA	Streptococcus mitis SK321	57.939	98.356	0.57
comA	Streptococcus pneumoniae TIGR4	57.66	98.356	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	56.825	98.356	0.559
comA/nlmT	Streptococcus mutans UA159	54.709	98.904	0.541