Detailed information NTG1162646

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AABJ29_RS10440
• Genome accession: NZ_OZ004876
• Coordinates: 1999693..2000880 (+)
• Length: 395 a.a.
• NCBI ID: WP_134921524.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae isolate 632_2023
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1994693..2005880

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ29_RS10425	-	1995613..1996212 (+)	600	WP_260237089.1	DUF4390 domain-containing protein	-
AABJ29_RS10430	-	1996212..1998332 (+)	2121	WP_260237090.1	sensor histidine kinase	-
AABJ29_RS10435	-	1998325..1999602 (+)	1278	WP_003690124.1	sigma-54-dependent transcriptional regulator	-
AABJ29_RS10440	dprA	1999693..2000880 (+)	1188	WP_134921524.1	DNA-processing protein DprA	Machinery gene
AABJ29_RS10445	-	2000906..2001367 (+)	462	WP_003690120.1	DUF494 domain-containing protein	-
AABJ29_RS10450	topA	2001439..2003745 (+)	2307	WP_260237091.1	type I DNA topoisomerase	-
AABJ29_RS10455	-	2003966..2004094 (+)	129	Protein_2029	phosphomethylpyrimidine synthase ThiC	-
AABJ29_RS10460	-	2004084..2004616 (+)	533	Protein_2030	IS1595 family transposase	-
AABJ29_RS10465	-	2004727..2005560 (+)	834	WP_338361980.1	opacity family porin	-
AABJ29_RS10470	-	2005574..2005768 (+)	195	WP_338361981.1	hypothetical protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41847.90 Da
• Isoelectric Point: 6.2394

>NTDB_id=1162646 AABJ29_RS10440 WP_134921524.1 1999693..2000880(+) (dprA) [Neisseria gonorrhoeae isolate 632_2023]
MTEDERFAWLQLAFTPYIGAESFLLLMRSFGSAQNALSAPAEQVAPAVRHKHALEAWHNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPTVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPVHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=1162646 AABJ29_RS10440 WP_134921524.1 1999693..2000880(+) (dprA) [Neisseria gonorrhoeae isolate 632_2023]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCAGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCCGGCGGTGCGGCATAAGCACGCGC
TTGAGGCTTGGCACAATGCAGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCTACCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GGCCAACAAAAACCTTGCTTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTCATGGCGGTGCCCGGTTCGATAGACAACCCCCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGAGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCGGTTCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCCATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (341-388)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae strain FA1090	99.494	100	0.995
dprA	Neisseria gonorrhoeae MS11	99.241	100	0.992
dprA	Neisseria meningitidis strain C311	90.176	100	0.906
dprA	Neisseria meningitidis MC58	90.176	100	0.906
dprA	Vibrio cholerae strain A1552	37.28	100	0.375