Detailed information NTG1162144

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: U9966_RS03035
• Genome accession: NZ_OY856306
• Coordinates: 633541..634614 (+)
• Length: 357 a.a.
• NCBI ID: WP_306346336.1
• Uniprot ID: -
• Organism: Pasteurella atlantica isolate PAF6K1
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 628541..639614

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U9966_RS03015	-	629104..631683 (-)	2580	WP_306346340.1	penicillin-binding protein 1A	-
U9966_RS03020	-	631793..632536 (+)	744	WP_306346339.1	hypothetical protein	-
U9966_RS03025	-	632518..633030 (+)	513	WP_306346338.1	hypothetical protein	-
U9966_RS03030	-	633177..633536 (+)	360	WP_306346337.1	hypothetical protein	-
U9966_RS03035	comE	633541..634614 (+)	1074	WP_306346336.1	type IV pilus secretin PilQ	Machinery gene
U9966_RS03040	-	634664..634870 (+)	207	WP_211599086.1	hypothetical protein	-
U9966_RS03045	nusB	635102..635515 (+)	414	WP_211599085.1	transcription antitermination factor NusB	-
U9966_RS03050	thiL	635526..636479 (+)	954	WP_306346335.1	thiamine-phosphate kinase	-
U9966_RS03055	-	636501..636983 (+)	483	WP_306346334.1	phosphatidylglycerophosphatase A	-
U9966_RS03060	-	637035..637949 (-)	915	WP_306346333.1	YiiG family protein	-
U9966_RS03065	-	638275..638895 (+)	621	WP_306346332.1	LysE family transporter	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39571.41 Da
• Isoelectric Point: 6.3096

>NTDB_id=1162144 U9966_RS03035 WP_306346336.1 633541..634614(+) (comE) [Pasteurella atlantica isolate PAF6K1]
MKKLVLLMCLFLSCYIYADPFYKEKEIMDNKVTVEEYNIDESEPDIVDKEGLVKSIHLNYARAKDIIESLTKGQGTLLDG
GYIHFDQQTNTLILKGSNRILNKLTALVKKLDKPIRQVAIEARVVTISSEHLQELGVRWGMFSPTANSHQFGGKLEGNGF
SANNLNVNFPVVSNAASAVIQIASLNNRLLDLELTALEQENSVEIIASPSLITTNENKASIKQGTEVAYPQRNAKGDITD
VEFRDAVLGLEVTPHFSQNDQILLDLLVTQNAPNTATASSQQWVTIDKQEIKTQVLAQNGKTIVLGGIFQNMLSKEKDAV
PLLGSLPILKHLFSHTKDKVAKRELVIFVTPHIINPQ

Nucleotide

• Length: 1074 bp

>NTDB_id=1162144 U9966_RS03035 WP_306346336.1 633541..634614(+) (comE) [Pasteurella atlantica isolate PAF6K1]
ATGAAAAAGTTAGTATTGTTAATGTGTTTGTTTTTGAGTTGTTATATTTATGCTGATCCTTTTTATAAAGAAAAAGAAAT
TATGGATAACAAAGTCACAGTTGAAGAATATAATATAGATGAAAGTGAACCTGATATTGTTGATAAAGAGGGTTTAGTAA
AAAGCATTCATTTAAATTATGCGAGAGCAAAAGATATTATTGAAAGTTTAACTAAAGGACAAGGAACCTTGTTAGATGGC
GGTTATATTCATTTTGATCAACAAACAAATACATTGATTTTAAAAGGAAGTAATCGGATTTTAAATAAATTAACCGCATT
AGTAAAAAAATTAGATAAACCCATTAGGCAAGTTGCTATTGAAGCAAGAGTAGTGACTATCAGTAGTGAACATTTACAAG
AATTAGGTGTTCGATGGGGAATGTTTAGTCCAACTGCAAACTCTCATCAATTTGGTGGAAAATTAGAAGGGAATGGGTTT
TCAGCAAATAATTTAAATGTTAATTTTCCAGTGGTCAGCAATGCAGCTTCTGCAGTTATTCAAATTGCGAGTTTGAACAA
TAGATTATTAGATCTAGAATTAACAGCATTAGAACAAGAAAATAGTGTGGAAATTATTGCTAGTCCAAGTTTAATTACAA
CAAATGAGAATAAAGCGAGTATCAAGCAAGGAACAGAGGTTGCTTATCCACAGCGTAATGCTAAAGGGGATATTACTGAT
GTTGAATTTCGTGATGCAGTTTTAGGGCTTGAAGTTACTCCTCATTTTTCTCAAAATGATCAAATTTTACTGGATTTATT
AGTTACTCAAAACGCACCAAATACAGCAACAGCAAGTAGTCAGCAATGGGTGACTATAGATAAACAAGAAATTAAAACAC
AGGTTTTAGCTCAAAATGGTAAAACGATTGTACTTGGAGGGATCTTTCAAAATATGCTTTCTAAGGAAAAAGATGCAGTA
CCTTTATTAGGAAGCCTACCGATATTAAAGCATTTATTTAGTCATACCAAAGATAAGGTGGCTAAACGTGAACTCGTCAT
TTTTGTCACGCCACATATAATTAATCCTCAGTAG

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (53-117)

• Bacterial type II and III secretion system protein (Secretin) (196-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Glaesserella parasuis strain SC1401	60.261	85.994	0.518
comE	Haemophilus influenzae Rd KW20	52.174	90.196	0.471
comE	Haemophilus influenzae 86-028NP	51.553	90.196	0.465
pilQ	Vibrio campbellii strain DS40M4	42.593	90.756	0.387
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	43.671	88.515	0.387
pilQ	Vibrio cholerae strain A1552	43.671	88.515	0.387