Detailed information NTG1161736

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: U8955_RS08305
• Genome accession: NZ_OY769914
• Coordinates: 1637844..1638581 (-)
• Length: 245 a.a.
• NCBI ID: WP_038804519.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1632844..1643581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8955_RS08290 (SDENT7746_08320)	-	1634874..1636235 (+)	1362	WP_038804515.1	bacteriocin secretion accessory protein	-
U8955_RS08295 (SDENT7746_08325)	blpC	1636292..1636447 (+)	156	WP_038804516.1	quorum-sensing system pheromone BlpC	-
U8955_RS08300 (SDENT7746_08330)	-	1636490..1637830 (-)	1341	WP_038804518.1	sensor histidine kinase	-
U8955_RS08305 (SDENT7746_08335)	comE/blpR	1637844..1638581 (-)	738	WP_038804519.1	response regulator transcription factor	Regulator
U8955_RS08310 (SDENT7746_08340)	-	1638586..1638924 (-)	339	WP_038804520.1	LytTR family DNA-binding domain-containing protein	-
U8955_RS08315 (SDENT7746_08345)	-	1639203..1639532 (+)	330	WP_038804521.1	hypothetical protein	-
U8955_RS08320 (SDENT7746_08350)	-	1639697..1640746 (-)	1050	WP_038804522.1	ABC transporter permease	-
U8955_RS08325 (SDENT7746_08355)	pptA	1640743..1641474 (-)	732	WP_038804523.1	ABC transporter ATP-binding protein	Regulator
U8955_RS08330 (SDENT7746_08360)	-	1641542..1641952 (+)	411	WP_038804524.1	HIT family protein	-
U8955_RS08335 (SDENT7746_08365)	-	1641962..1642240 (+)	279	WP_000777742.1	hypothetical protein	-
U8955_RS08340 (SDENT7746_08370)	-	1642304..1642963 (+)	660	WP_038804526.1	hypothetical protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28813.97 Da
• Isoelectric Point: 6.0460

>NTDB_id=1161736 U8955_RS08305 WP_038804519.1 1637844..1638581(-) (comE/blpR) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MRIFVLEDDFSQQTRIETTIEKLLKEHHIIPSSFEVFGKPDQLLAEMHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKSLSAEEFESRIETALLYADSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide

• Length: 738 bp

>NTDB_id=1161736 U8955_RS08305 WP_038804519.1 1637844..1638581(-) (comE/blpR) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAGAATATTTGTTTTAGAAGATGATTTCTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAAGAACA
TCATATCATTCCCAGCTCTTTTGAAGTCTTTGGCAAGCCAGACCAACTTCTGGCAGAGATGCATGAGAAGGGAGCACATC
AGCTATTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAAGGCCTAGAAGTGGCAAGAAAGATTCGGGATCGAGAT
CCTTATGCCCTGATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGTCCTTGTCGGCGGAGGAGTTTGAGTCTCGTATCGAGACAGCTCTTCTCTATGCCGATAGTCAAGACA
GCAAAAGCCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCTCCTAGAGCCCATCGTGTTATTCTCTATACCAAGACGGATAGACTGGAATTTACGGCGAGCCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGTCATCGTTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTTAGGGAAGTTTCTGAGGCT
ATCAATAATTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-241)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	43.46	96.735	0.42
comE/comE2	Streptococcus equinus JB1	38.43	98.776	0.38
comE	Streptococcus infantis strain Atu-4	36.179	100	0.363