Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   U8955_RS05855 Genome accession   NZ_OY769914
Coordinates   1167028..1167876 (-) Length   282 a.a.
NCBI ID   WP_038805368.1    Uniprot ID   A0A7T3DY21
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1162028..1172876
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS05835 (SDENT7746_05875) - 1162932..1163588 (-) 657 WP_038805364.1 MmcQ/YjbR family DNA-binding protein -
  U8955_RS05840 (SDENT7746_05880) - 1163632..1164264 (-) 633 WP_038805365.1 copper homeostasis protein CutC -
  U8955_RS05845 (SDENT7746_05885) - 1164357..1164716 (-) 360 WP_001220344.1 YbaN family protein -
  U8955_RS05850 (SDENT7746_05890) topA 1164822..1166909 (-) 2088 WP_038805367.1 type I DNA topoisomerase -
  U8955_RS05855 (SDENT7746_05895) dprA/cilB/dalA 1167028..1167876 (-) 849 WP_038805368.1 DNA-processing protein DprA Machinery gene
  U8955_RS05860 (SDENT7746_05900) lepA 1168043..1169866 (-) 1824 WP_038805369.1 translation elongation factor 4 -
  U8955_RS05865 (SDENT7746_05905) - 1169945..1170673 (-) 729 WP_038805370.1 metallophosphoesterase family protein -
  U8955_RS05870 (SDENT7746_05910) recN 1170674..1172341 (-) 1668 WP_038805371.1 DNA repair protein RecN -
  U8955_RS05875 (SDENT7746_05915) - 1172348..1172779 (-) 432 WP_038805372.1 arginine repressor -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31289.74 Da        Isoelectric Point: 5.0673

>NTDB_id=1161726 U8955_RS05855 WP_038805368.1 1167028..1167876(-) (dprA/cilB/dalA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVDQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPALLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQKVIQGLENELIVVSGLAKGIDTAAHMAELQNGGR
TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=1161726 U8955_RS05855 WP_038805368.1 1167028..1167876(-) (dprA/cilB/dalA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAAGATCACAAACTATGAGATTTACAAATTGAGAAAAGCTGGACTGACCAATCAACAAATTTTAACAGTTCTTGAATA
TGACGAGACTGTAGATCAGGAGCTCTTGCTAGGTGATATTGCTGAAATATCTGGGTGCCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTCCAAAAATTTCCATCCTTCTCGATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGCGCTCTTGTTTTATAAAGGAAATCTGGACTTGTTGAAGTTTCC
AAAGGTTGCTGTTGTAGGGAGTCGTTCATGTTCTAGTCAGGGAGCAAAGTCGGTTCAGAAAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTGGTCAGTGGTTTAGCCAAAGGGATTGATACGGCTGCCCATATGGCTGAACTCCAAAATGGAGGAAGA
ACGATTGCTGTCATTGGAACAGGGTTGGATGTTTTTTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAGTACGGACCTGGTGAAGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGAATCATAGCAG
GACTGTGTCGCGGCGTTATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTCATCACTTGTGAGCGAGCTATGGAGGAA
GGGCGTGATGTTTTTGCCATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC
AAAGCTGATTTCCAGTGGTCAAGATGTGCTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DY21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

91.135

100

0.911
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

90.78

100

0.908
  dprA/cilB/dalA Streptococcus pneumoniae D39

90.78

100

0.908
  dprA/cilB/dalA Streptococcus pneumoniae R6

90.78

100

0.908
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

90.78

100

0.908
  dprA/cilB/dalA Streptococcus mitis SK321

90.071

100

0.901
  dprA Streptococcus mutans UA159

60.714

99.291

0.603
  dprA Lactococcus lactis subsp. cremoris KW2

54.286

99.291

0.539

Multiple sequence alignment