Detailed information NTG1161720

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: U8955_RS04260
• Genome accession: NZ_OY769914
• Coordinates: 839141..840097 (+)
• Length: 318 a.a.
• NCBI ID: WP_038805095.1
• Uniprot ID: A0A7T2ZVK4
• Organism: Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 834141..845097

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8955_RS04245 (SDENT7746_04260)	smpB	836399..836866 (+)	468	WP_001051742.1	SsrA-binding protein SmpB	-
U8955_RS04250 (SDENT7746_04265)	tehB	836881..837741 (+)	861	WP_000413063.1	SAM-dependent methyltransferase TehB	-
U8955_RS04255 (SDENT7746_04270)	-	837919..839066 (+)	1148	Protein_798	hypothetical protein	-
U8955_RS04260 (SDENT7746_04275)	coiA	839141..840097 (+)	957	WP_038805095.1	competence protein CoiA	Machinery gene
U8955_RS04265 (SDENT7746_04280)	pepF	840116..841918 (+)	1803	WP_038805096.1	oligoendopeptidase F	Regulator
U8955_RS04270 (SDENT7746_04285)	-	841920..842633 (+)	714	WP_068981916.1	O-methyltransferase	-
U8955_RS04275 (SDENT7746_04290)	-	842681..843304 (+)	624	WP_038805097.1	recombinase family protein	-
U8955_RS04280 (SDENT7746_04295)	-	843610..844761 (+)	1152	WP_050562297.1	LPXTG cell wall anchor domain-containing protein	-

Sequence

Protein

• Length: 318 a.a.
• Molecular weight: 37834.36 Da
• Isoelectric Point: 9.4778

>NTDB_id=1161720 U8955_RS04260 WP_038805095.1 839141..840097(+) (coiA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MFVARDAKGNLVNALEKDVTKQPYTCPVCGGGLRLRQGQSVRTHFAHERLRDCIAIFENESPEHLGNKEALYHWAKKDSQ
VALEYSLPEIQQIADVLVNEKLALEVQCSPLSQKILGDRSQGYRSQGYQVIWLLGEKLWLKERLTQLQRGFLYFSQNMGF
YVWELDLKRKILRLKYLLHQDLRGKLHFQVKEFPYGQGNLLEILRFPYQKQKLPHFAVVQDSSICHYIRQQLYYQTPYWM
KKQEEAYQQGDNLLNRQLDDWYPQVRPIASGDFLQIETDLTSYYRNFQAYYQKNPKNNRQKLYPPAFYHLYFSRNMVK

Nucleotide

• Length: 957 bp

>NTDB_id=1161720 U8955_RS04260 WP_038805095.1 839141..840097(+) (coiA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGTTTGTAGCCAGAGATGCCAAGGGAAATTTGGTGAATGCCCTCGAAAAAGATGTGACCAAGCAGCCTTACACCTGCCC
AGTTTGTGGGGGCGGACTACGCTTACGCCAAGGACAGAGTGTTCGAACGCACTTTGCCCATGAAAGGTTAAGGGATTGTA
TCGCTATTTTCGAGAATGAAAGTCCAGAACACTTAGGCAACAAAGAGGCCCTTTATCACTGGGCCAAGAAGGACAGTCAG
GTCGCCTTAGAATATAGTTTGCCCGAGATTCAGCAGATAGCGGATGTTCTCGTCAATGAGAAACTAGCTCTGGAGGTTCA
GTGTAGTCCCTTGTCTCAAAAGATTTTAGGCGATAGAAGCCAAGGATACCGTAGCCAGGGCTATCAGGTTATCTGGCTAC
TGGGAGAAAAACTCTGGTTAAAAGAGCGATTAACACAACTGCAAAGGGGATTTCTCTATTTTAGTCAAAATATGGGTTTC
TATGTTTGGGAACTGGATCTCAAAAGGAAAATTTTGAGACTCAAATATCTTCTGCATCAGGATCTACGTGGCAAGCTTCA
TTTTCAGGTCAAGGAATTTCCCTATGGCCAAGGAAATCTCTTGGAAATTCTACGATTTCCTTATCAAAAACAAAAACTGC
CTCATTTTGCAGTTGTACAAGATTCATCTATCTGTCACTACATTCGTCAGCAGTTGTACTACCAAACGCCTTACTGGATG
AAGAAGCAGGAGGAGGCCTATCAGCAAGGAGACAATCTATTAAACCGTCAACTGGACGACTGGTATCCCCAGGTCAGACC
GATAGCATCAGGTGATTTTTTGCAGATTGAAACGGATCTGACTAGCTATTATAGAAATTTTCAGGCATACTATCAAAAAA
ATCCGAAAAATAATCGCCAAAAGCTCTATCCACCAGCCTTTTATCACTTATATTTCTCAAGAAATATGGTAAAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-248)

3D structure

• AlphaFold DB: A0A7T2ZVK4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	70.755	100	0.708
coiA	Streptococcus pneumoniae D39	70.755	100	0.708
coiA	Streptococcus pneumoniae R6	70.755	100	0.708
coiA	Streptococcus pneumoniae TIGR4	70.44	100	0.704
coiA	Streptococcus mitis NCTC 12261	70.44	100	0.704
coiA	Lactococcus lactis subsp. cremoris KW2	42.769	100	0.437