Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   U8955_RS04265 Genome accession   NZ_OY769914
Coordinates   840116..841918 (+) Length   600 a.a.
NCBI ID   WP_038805096.1    Uniprot ID   A0A7T2ZWM7
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 835116..846918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS04245 (SDENT7746_04260) smpB 836399..836866 (+) 468 WP_001051742.1 SsrA-binding protein SmpB -
  U8955_RS04250 (SDENT7746_04265) tehB 836881..837741 (+) 861 WP_000413063.1 SAM-dependent methyltransferase TehB -
  U8955_RS04255 (SDENT7746_04270) - 837919..839066 (+) 1148 Protein_798 hypothetical protein -
  U8955_RS04260 (SDENT7746_04275) coiA 839141..840097 (+) 957 WP_038805095.1 competence protein CoiA Machinery gene
  U8955_RS04265 (SDENT7746_04280) pepF 840116..841918 (+) 1803 WP_038805096.1 oligoendopeptidase F Regulator
  U8955_RS04270 (SDENT7746_04285) - 841920..842633 (+) 714 WP_068981916.1 O-methyltransferase -
  U8955_RS04275 (SDENT7746_04290) - 842681..843304 (+) 624 WP_038805097.1 recombinase family protein -
  U8955_RS04280 (SDENT7746_04295) - 843610..844761 (+) 1152 WP_050562297.1 LPXTG cell wall anchor domain-containing protein -
  U8955_RS04285 (SDENT7746_04300) prsA 844952..845893 (+) 942 WP_038805098.1 peptidylprolyl isomerase PrsA -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69805.81 Da        Isoelectric Point: 4.6738

>NTDB_id=1161721 U8955_RS04265 WP_038805096.1 840116..841918(+) (pepF) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MVLQRHEINEKDTWDLSTIYPTDHAWEEALKDLTEKVQTAAQYEGHLLDSADSLLEITEFSLDLERQVEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLEQAFSFYEPEFMEISEEQYAAFLEAQPKLQVYKHFFDKLLQKKDHVLSQREEELLAGA
GEIFGAASETFAILDNADISFPYVLDDEGKEVQLSHSTYIRLMESKNREVRRGAYEALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLKLRSKILGISDLKMYDVYTPLSSVDYSFTYEEALK
KAEEALAVLGDDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPQIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1161721 U8955_RS04265 WP_038805096.1 840116..841918(+) (pepF) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGGTATTACAACGACATGAAATAAATGAAAAAGATACATGGGATCTTTCAACAATCTACCCAACAGATCATGCTTGGGA
AGAAGCCTTGAAAGACTTAACTGAAAAAGTACAAACAGCAGCCCAGTATGAGGGGCATCTCTTGGATAGCGCAGACAGTT
TGCTTGAGATTACAGAATTCTCACTTGACTTGGAACGCCAAGTTGAAAAGCTTTATGTCTATGCGCATATGAAAAATGAC
CAGGACACGCGTGAGGCCAAGTATCAAGAGTACTATGCTAAGGCAATGACCCTATACAGTCAGTTAGAACAAGCCTTTTC
ATTCTATGAACCTGAGTTTATGGAGATTAGTGAAGAGCAGTATGCGGCCTTCCTAGAAGCTCAACCAAAACTCCAAGTTT
ACAAGCACTTTTTTGACAAGCTCTTGCAAAAGAAAGACCATGTTCTTTCGCAACGTGAGGAAGAATTGCTTGCTGGAGCA
GGAGAAATCTTTGGCGCTGCTAGTGAAACCTTCGCTATTTTGGACAACGCGGATATTAGCTTCCCATATGTCCTTGATGA
CGAAGGCAAGGAAGTGCAACTCTCACACAGTACTTACATTCGCTTGATGGAGTCTAAAAACCGTGAGGTGCGCCGTGGTG
CCTATGAAGCCCTTTATGCGACTTATGAGCAATTCCAGCATACTTACGCTAAGACTTTGCAGACAAATGTTAAGGTGCAA
AACTACCGCGCAAAAGTTCGTAACTATAAGAGTGCTCGCCATGCAGCCCTCGCAGCAAATTTTGTTCCAGAAAGTGTCTA
TGACAATCTAGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGTTACCTTAAACTTCGTTCTAAAATCTTGGGGA
TTTCAGATCTCAAGATGTATGATGTCTACACTCCGCTCTCGTCAGTAGATTATAGCTTTACTTACGAAGAAGCCTTGAAA
AAGGCAGAAGAGGCCTTGGCGGTCTTGGGTGACGACTACTTGAGCCGTGTTAAACGGGCCTTCAGTGAGCGTTGGATTGA
TGTCTATGAAAATCAAGGCAAGCGTTCTGGTGCCTACTCTGGTGGTTCATACGATACCAATGCCTTTATGCTCCTCAACT
GGCAGGACAATCTAGACAATCTCTTTACCCTTGTCCATGAAACAGGTCATAGTATGCACTCAAGCTATACTCGTGAAACC
CAACCATATGTTTACGGGGATTATTCTATCTTCTTGGCAGAGATTGCCTCAACGACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAGGAAGTGGAAGACGATGCAACTCGCTTTGCTATTCTCAATAACTTCCTAGACGGTTTCCGTGGAACAGTCT
TCCGTCAAACTCAATTCGCTGAGTTTGAACACGCCATCCACCAAGCAGACCAAAATGGAGAAGTCTTGACAAGTGATTTC
CTCAATAAACTCTACGCTGACTTGAACCAAGAGTACTATGGACTCAGCAAGGAAGACAATCCTCAAATCCAATACGAGTG
GGCGCGCATTCCACACTTCTACTATAACTACTACGTATACCAGTATTCGACTGGTTTTGCAGCGGCTTCAGCCTTGGCTG
AGAAGATTGTCCATGGTAGTCAGGAAGACCGTGACCGTTATATCGACTACCTCAAGGCAGGTAAGTCAGACTATCCACTC
AATGTCATGAGAAAAGCGGGAGTAGATATGGAGAAGGAAGACTATCTCAACGACGCCTTTGCAGTCTTTGAACGCCGCTT
GAATGAGTTTGAAGCCTTAGTTGAAAAATTGGGACTAGCTTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZWM7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.114

99.333

0.667

Multiple sequence alignment