Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   QOR45_RS02225 Genome accession   NZ_OX460935
Coordinates   385065..387020 (+) Length   651 a.a.
NCBI ID   WP_283572066.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate MRI Z2-286     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 380065..392020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR45_RS02210 fmt 382043..382978 (+) 936 WP_000163893.1 methionyl-tRNA formyltransferase -
  QOR45_RS02215 rsmB 382968..384290 (+) 1323 WP_001262608.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QOR45_RS02220 - 384328..385065 (+) 738 WP_283572065.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QOR45_RS02225 pknB 385065..387020 (+) 1956 WP_283572066.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QOR45_RS02230 liaF 387181..387882 (+) 702 WP_283572067.1 cell wall-active antibiotics response protein LiaF -
  QOR45_RS02235 - 387879..388898 (+) 1020 WP_283572068.1 sensor histidine kinase -
  QOR45_RS02240 - 388891..389532 (+) 642 WP_000357891.1 response regulator transcription factor -
  QOR45_RS02245 - 389574..390974 (+) 1401 WP_000339135.1 Cof-type HAD-IIB family hydrolase -
  QOR45_RS02250 - 390976..391332 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 70797.55 Da        Isoelectric Point: 9.6145

>NTDB_id=1158972 QOR45_RS02225 WP_283572066.1 385065..387020(+) (pknB) [Streptococcus agalactiae isolate MRI Z2-286]
MIQIGKLFAGRYRILKSIGRGGMADVYLARDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELTHPNIVAIRDIG
EEDGQQFLVMEYVDGFDLKKYIQDNAPLSNNEVVRIMNEVLSAMSLAHQKGIVHRDLKPQNILLTKKGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENKSVP
QALENIVIKATAKKLTDRYKTTYEMGRDLSTALSSTRHREPKLVFNDTESTKTLPKVTSTVSSLTTEQLLRNQKEAKTTE
KITPDSASNDKTKSKKKASHRLLGTIMKLFFALCVVGIIVFAYKILVSPTTIRVPDVSNKTVAQAKMTLENSGLKVGAIR
NIENDSVSEGLVVKTDPAAGRSRREGAKVNLYIATPNKSFTLGNYKEHNYKDILKDLQGKGVKKSLIKVKRKINNDYTTG
TILAQSLPEGTSFNPDGNKKLTLTVAVNDPMIMPDVTGMTVGEVIETLTDLGLDADNLVFYQMQNGVYQAVVTPPSSSKI
ASQDPYYGGEVGLRRGDKVKLYLLGSKTTNNSSSTPIDSSASSSTGTTTSDSVSSSTDASTSDSSSTSTSSSTLPSDSTT
NTGTANNPLTQ

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=1158972 QOR45_RS02225 WP_283572066.1 385065..387020(+) (pknB) [Streptococcus agalactiae isolate MRI Z2-286]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTTAAATCAATCGGACGAGGTGGAATGGCGGATGTTTA
TCTAGCTCGAGATCTAATTTTAGATAATGAAGAGGTCGCAATAAAAGTATTGCGAACCAATTATCAAACAGATCAGATTG
CGGTTGCTCGCTTCCAGAGAGAAGCACGAGCAATGGCTGAGCTGACACATCCTAATATTGTCGCTATTCGTGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATGTTGATGGATTCGATTTAAAAAAGTATATTCAAGACAATGCACC
CCTATCAAATAATGAAGTTGTTCGAATCATGAATGAAGTCCTTTCAGCCATGTCGCTGGCACATCAGAAAGGTATCGTAC
ACCGTGATTTAAAACCTCAAAATATTTTATTAACTAAAAAAGGGACTGTAAAAGTTACAGATTTCGGTATTGCGGTAGCG
TTTGCTGAAACTAGTTTAACGCAAACGAATTCTATGTTAGGTAGTGTTCATTATTTATCGCCAGAGCAGGCGCGTGGTTC
AAAAGCGACTGTTCAGAGTGATATTTATGCCATGGGAATCATGCTTTTTGAAATGTTAACTGGCCATATTCCTTATGATG
GGGATAGTGCAGTTACTATTGCCCTACAGCACTTCCAAAAACCACTACCATCAATCCTTGCAGAAAATAAAAGCGTTCCA
CAAGCTTTGGAAAACATTGTCATTAAAGCAACAGCTAAAAAGCTAACAGATCGCTATAAGACAACTTATGAGATGGGACG
TGATTTATCAACTGCTCTAAGCTCGACACGTCATCGTGAACCAAAACTTGTTTTTAATGATACTGAGAGTACTAAGACAC
TACCCAAAGTAACATCTACAGTATCATCTCTAACGACAGAACAACTGTTGCGTAATCAAAAAGAGGCCAAAACAACAGAA
AAAATAACTCCTGATTCTGCGAGTAACGATAAAACGAAGTCTAAAAAGAAGGCTTCTCATCGACTTCTTGGTACAATCAT
GAAATTATTCTTTGCACTCTGTGTTGTAGGAATAATTGTATTTGCTTATAAAATTTTAGTAAGTCCTACGACTATTCGTG
TTCCAGATGTTAGCAACAAAACAGTAGCTCAAGCAAAAATGACATTGGAAAATTCTGGATTGAAAGTAGGAGCTATTCGT
AATATTGAGAATGATAGTGTTTCAGAAGGCCTTGTCGTAAAAACAGACCCTGCTGCAGGACGTTCTCGTAGAGAAGGGGC
TAAAGTTAATCTTTATATTGCCACTCCAAACAAGAGTTTCACTCTAGGTAATTATAAGGAACATAATTACAAAGATATCC
TCAAAGATCTTCAAGGCAAAGGTGTTAAAAAATCTTTAATCAAGGTTAAGCGTAAAATTAATAATGATTATACTACTGGT
ACAATCTTAGCACAGTCGCTTCCAGAAGGAACATCTTTTAATCCTGATGGTAATAAGAAATTAACACTTACGGTTGCTGT
TAATGATCCAATGATTATGCCTGATGTAACAGGTATGACAGTTGGAGAAGTAATAGAAACCTTGACAGACCTCGGATTAG
ATGCAGATAATCTTGTCTTCTATCAAATGCAAAATGGCGTTTATCAAGCAGTAGTAACACCTCCATCCTCAAGTAAGATA
GCAAGTCAGGATCCTTATTACGGAGGAGAAGTTGGATTAAGGAGAGGAGATAAGGTTAAGCTGTATCTTCTTGGTTCTAA
AACAACGAATAACTCATCATCTACGCCAATAGATTCTTCGGCTTCAAGCTCAACAGGAACAACTACCTCGGATTCTGTAA
GCTCATCAACGGATGCTAGCACTTCTGATAGTAGTAGCACTTCTACAAGTAGTTCAACGCTACCAAGTGATAGTACAACT
AATACAGGAACAGCTAACAATCCATTAACTCAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(441-506)

Protein kinase domain (Pkinase)

(12-254)

PASTA domain (PASTA)

(511-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

60.959

89.708

0.547
  stkP/pknB Streptococcus salivarius strain HSISS4

60.9

88.786

0.541
  stkP Streptococcus pneumoniae TIGR4

59.921

78.187

0.469
  stkP Streptococcus pneumoniae D39

59.725

78.187

0.467
  stkP Streptococcus pneumoniae R6

59.725

78.187

0.467
  stkP Streptococcus pneumoniae Rx1

59.528

78.187

0.465

Multiple sequence alignment