Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   QOR56_RS01915 Genome accession   NZ_OX460906
Coordinates   339610..341565 (+) Length   651 a.a.
NCBI ID   WP_283573722.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate MRI Z2-265     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 334610..346565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR56_RS01900 fmt 336588..337523 (+) 936 WP_283573721.1 methionyl-tRNA formyltransferase -
  QOR56_RS01905 rsmB 337513..338835 (+) 1323 WP_001262608.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QOR56_RS01910 - 338873..339610 (+) 738 WP_283572065.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QOR56_RS01915 pknB 339610..341565 (+) 1956 WP_283573722.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QOR56_RS01920 liaF 341726..342427 (+) 702 WP_283572067.1 cell wall-active antibiotics response protein LiaF -
  QOR56_RS01925 - 342424..343443 (+) 1020 WP_283572068.1 sensor histidine kinase -
  QOR56_RS01930 - 343436..344077 (+) 642 WP_000357891.1 response regulator transcription factor -
  QOR56_RS01935 - 344119..345519 (+) 1401 WP_000339135.1 Cof-type HAD-IIB family hydrolase -
  QOR56_RS01940 - 345521..345877 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 70801.54 Da        Isoelectric Point: 9.6145

>NTDB_id=1158725 QOR56_RS01915 WP_283573722.1 339610..341565(+) (pknB) [Streptococcus agalactiae isolate MRI Z2-265]
MIQIGKLFAGRYRILKSIGRGGMADVYLARDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELTHPNIVAIRDIG
EEDGQQFLVMEYVDGFDLKKYIQDNAPLSNNEVVRIMNEVLSAMSLAHQKGIVHRDLKPQNILLTKKGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENKSVP
QALENIVIKATAKKLTDRYKTTYEMGRDLSTALSSTRHREPKLVFNDTESTKTLPKVTSTVSSLTTEQLLRNQKEAKTTE
KITPDSASNDKTKSKKKASHRLLGTIMKLFFALCVVGIIVFAYKILVSPTTIRVPDVSNKTVAQAKMTLENSGLKVGAIR
NIENDSVSEGLVVKTDPAAGRSRREGAKVNLYIATPNKSFTLGNYKEHNYKDILKDLQGKGVKKSLIKVKRKINNDYTTG
TILAQSLPEGTSFNPDGNKKLTLTVAVNDPMIMPDVTGMTVGEVIETLTDLGLDADNLVFYQMQNGVYQAVVTPPSSSKI
ASQDTYYGGEVGLRRGDKVKLYLLGSKTTNNSSSTPIDSSASSSTGTTTSDSVSSSTDASTSDSSSTSTSSSTLPSDSTT
NTGTANNPLTQ

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=1158725 QOR56_RS01915 WP_283573722.1 339610..341565(+) (pknB) [Streptococcus agalactiae isolate MRI Z2-265]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTTAAATCAATCGGACGAGGTGGAATGGCGGATGTTTA
TCTAGCTCGAGATCTAATTTTAGATAATGAAGAGGTCGCAATAAAAGTATTGCGAACCAATTATCAAACAGATCAGATTG
CGGTTGCTCGCTTCCAGAGAGAAGCACGAGCAATGGCTGAGCTGACACATCCTAATATTGTCGCTATTCGTGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATGTTGATGGATTCGATTTAAAAAAGTATATTCAAGACAATGCACC
CCTATCAAATAATGAAGTTGTTCGAATCATGAATGAAGTCCTTTCAGCCATGTCGCTGGCACATCAGAAAGGTATCGTAC
ACCGTGATTTAAAACCTCAAAATATTTTATTAACTAAAAAAGGGACTGTAAAAGTTACAGATTTCGGTATTGCGGTAGCG
TTTGCTGAAACTAGTTTAACGCAAACGAATTCTATGTTAGGTAGTGTTCATTATTTATCGCCAGAGCAGGCGCGTGGTTC
AAAAGCGACTGTTCAGAGTGATATTTATGCCATGGGAATCATGCTTTTTGAAATGTTAACTGGCCATATTCCTTATGATG
GGGATAGTGCAGTTACTATTGCCCTACAGCACTTCCAAAAACCACTACCATCAATCCTTGCAGAAAATAAAAGCGTTCCA
CAAGCTTTGGAAAACATTGTCATTAAAGCAACAGCTAAAAAGCTAACAGATCGCTATAAGACAACTTATGAGATGGGACG
TGATTTATCAACTGCTCTAAGCTCGACACGTCATCGTGAACCAAAACTTGTTTTTAATGATACTGAGAGTACTAAGACAC
TACCCAAAGTAACATCTACAGTATCATCTCTAACGACAGAACAACTGTTGCGTAATCAAAAAGAGGCCAAAACAACAGAA
AAAATAACTCCTGATTCTGCGAGTAACGATAAAACGAAGTCTAAAAAGAAGGCTTCTCATCGACTTCTTGGTACAATCAT
GAAATTATTCTTTGCACTCTGTGTTGTAGGAATAATTGTATTTGCTTATAAAATTTTAGTAAGTCCTACGACTATTCGTG
TTCCAGATGTTAGCAACAAAACAGTAGCTCAAGCAAAAATGACATTGGAAAATTCTGGATTGAAAGTAGGAGCTATTCGT
AATATTGAGAATGATAGTGTTTCAGAAGGCCTTGTCGTAAAAACAGACCCTGCTGCAGGACGTTCTCGTAGAGAAGGGGC
TAAAGTTAATCTTTATATTGCCACTCCAAACAAGAGTTTCACTCTAGGTAATTATAAGGAACATAATTACAAAGATATCC
TCAAAGATCTTCAAGGCAAAGGTGTTAAAAAATCTTTAATCAAGGTTAAGCGTAAAATTAATAATGATTATACTACTGGT
ACAATCTTAGCACAGTCGCTTCCAGAAGGAACATCTTTTAATCCTGATGGTAATAAGAAATTAACACTTACGGTTGCTGT
TAATGATCCAATGATTATGCCTGATGTAACAGGTATGACAGTTGGAGAAGTAATAGAAACCTTGACAGACCTCGGATTAG
ATGCAGATAATCTTGTCTTCTATCAAATGCAAAATGGCGTTTATCAAGCAGTAGTAACACCTCCATCCTCAAGTAAGATA
GCAAGTCAGGATACTTATTACGGAGGAGAAGTTGGATTAAGGAGAGGAGATAAGGTTAAGCTGTATCTTCTTGGTTCTAA
AACAACGAATAACTCATCATCTACGCCAATAGATTCTTCGGCTTCAAGCTCAACAGGAACAACTACCTCGGATTCTGTAA
GCTCATCAACGGATGCTAGCACTTCTGATAGTAGTAGCACTTCTACAAGTAGTTCAACGCTACCAAGTGATAGTACAACT
AATACAGGAACAGCTAACAATCCATTAACTCAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-254)

PASTA domain (PASTA)

(441-506)

PASTA domain (PASTA)

(511-583)

PASTA domain (PASTA)

(373-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

60.788

89.708

0.545
  stkP/pknB Streptococcus salivarius strain HSISS4

60.727

88.786

0.539
  stkP Streptococcus pneumoniae TIGR4

59.921

78.187

0.469
  stkP Streptococcus pneumoniae D39

59.725

78.187

0.467
  stkP Streptococcus pneumoniae R6

59.725

78.187

0.467
  stkP Streptococcus pneumoniae Rx1

59.528

78.187

0.465

Multiple sequence alignment