Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   QNH65_RS00815 Genome accession   NZ_OX352940
Coordinates   164894..165598 (+) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis isolate 861160_LM_A     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 159894..170598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNH65_RS00795 - 161702..162361 (-) 660 WP_074400590.1 amino acid ABC transporter permease -
  QNH65_RS00800 - 162376..163074 (-) 699 WP_015646621.1 amino acid ABC transporter permease -
  QNH65_RS00805 - 163089..163928 (-) 840 WP_023369690.1 transporter substrate-binding domain-containing protein -
  QNH65_RS00810 - 163939..164700 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  QNH65_RS00815 micA 164894..165598 (+) 705 WP_002935840.1 response regulator YycF Regulator
  QNH65_RS00820 micB 165591..166940 (+) 1350 WP_024405653.1 cell wall metabolism sensor histidine kinase VicK Regulator
  QNH65_RS00825 vicX 166947..167750 (+) 804 WP_023369694.1 MBL fold metallo-hydrolase Regulator
  QNH65_RS00830 - 168112..168492 (+) 381 Protein_151 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=1155443 QNH65_RS00815 WP_002935840.1 164894..165598(+) (micA) [Streptococcus suis isolate 861160_LM_A]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1155443 QNH65_RS00815 WP_002935840.1 164894..165598(+) (micA) [Streptococcus suis isolate 861160_LM_A]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment