Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   QNH74_RS07785 Genome accession   NZ_OX352806
Coordinates   1579050..1581044 (-) Length   664 a.a.
NCBI ID   WP_004194142.1    Uniprot ID   -
Organism   Streptococcus suis isolate 861160_dxerD_hsdSA     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1574050..1586044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNH74_RS07760 - 1574486..1574857 (-) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  QNH74_RS07765 - 1574859..1576259 (-) 1401 WP_074389960.1 Cof-type HAD-IIB family hydrolase -
  QNH74_RS07770 - 1576309..1576950 (-) 642 WP_024394813.1 response regulator transcription factor -
  QNH74_RS07775 - 1576922..1577938 (-) 1017 WP_074389959.1 sensor histidine kinase -
  QNH74_RS07780 liaF 1577935..1578594 (-) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  QNH74_RS07785 stkP 1579050..1581044 (-) 1995 WP_004194142.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QNH74_RS07790 - 1581044..1581781 (-) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QNH74_RS07795 rsmB 1581819..1583132 (-) 1314 WP_074389958.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QNH74_RS07800 fmt 1583119..1584057 (-) 939 WP_011921989.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71560.17 Da        Isoelectric Point: 6.7857

>NTDB_id=1155375 QNH74_RS07785 WP_004194142.1 1579050..1581044(-) (stkP) [Streptococcus suis isolate 861160_dxerD_hsdSA]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KSPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIATGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSRNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=1155375 QNH74_RS07785 WP_004194142.1 1579050..1581044(-) (stkP) [Streptococcus suis isolate 861160_dxerD_hsdSA]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTTGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGGTCTGTTCACTATCTTTCACCTGAGCAAGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGGATTATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCC
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGACCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCTCAAGCCAATGTTGAAACGAAAGTACCGCATACAAATAGTTCCGCCCAAGTTTCTGCGACAGAT
AAGAGCCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGACTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCACGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTATGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTCGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAACAGGAAGTTCCACAAGTACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-240)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(441-501)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.187

99.849

0.521
  stkP Streptococcus pneumoniae D39

52.036

99.849

0.52
  stkP Streptococcus pneumoniae R6

52.036

99.849

0.52
  stkP Streptococcus pneumoniae Rx1

51.885

99.849

0.518
  stkP/pknB Streptococcus salivarius strain HSISS4

52.479

88.102

0.462
  pknB Streptococcus mutans UA159

54.393

80.572

0.438

Multiple sequence alignment