Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QML74_RS02390 Genome accession   NZ_OX346404
Coordinates   464320..465567 (-) Length   415 a.a.
NCBI ID   WP_281957854.1    Uniprot ID   -
Organism   Enterococcus cecorum isolate CIRMBP-1281     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 459320..470567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML74_RS02355 (CIRMBP1281_00470) - 459604..459915 (+) 312 WP_016251466.1 thioredoxin family protein -
  QML74_RS02360 (CIRMBP1281_00471) - 459938..460381 (+) 444 WP_016251467.1 universal stress protein -
  QML74_RS02365 (CIRMBP1281_00472) - 460426..461028 (+) 603 WP_281957853.1 CadD family cadmium resistance transporter -
  QML74_RS02370 (CIRMBP1281_00473) ytpR 461107..461718 (+) 612 WP_047334171.1 YtpR family tRNA-binding protein -
  QML74_RS02375 (CIRMBP1281_00474) - 461786..461956 (-) 171 WP_168930749.1 hypothetical protein -
  QML74_RS02380 (CIRMBP1281_00475) - 461959..463188 (-) 1230 WP_047242911.1 MFS transporter -
  QML74_RS02385 (CIRMBP1281_00476) - 463557..464213 (+) 657 WP_047242864.1 Crp/Fnr family transcriptional regulator -
  QML74_RS02390 (CIRMBP1281_00477) htrA 464320..465567 (-) 1248 WP_281957854.1 trypsin-like peptidase domain-containing protein Regulator
  QML74_RS02395 (CIRMBP1281_00478) rlmH 466024..466503 (+) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QML74_RS02400 (CIRMBP1281_00479) - 466511..467209 (+) 699 WP_113785142.1 hydrolase -
  QML74_RS02405 (CIRMBP1281_00480) - 467357..468535 (+) 1179 WP_281958245.1 MalY/PatB family protein -
  QML74_RS02410 (CIRMBP1281_00481) - 468562..469662 (+) 1101 WP_281957855.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  QML74_RS02415 (CIRMBP1281_00482) - 469665..470414 (+) 750 WP_281957856.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43172.13 Da        Isoelectric Point: 5.2417

>NTDB_id=1155023 QML74_RS02390 WP_281957854.1 464320..465567(-) (htrA) [Enterococcus cecorum isolate CIRMBP-1281]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTETKVKNVKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGSLEDFFGAQQGNSSSQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDSLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPASLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGEKVNDGTALRAALYKKQVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=1155023 QML74_RS02390 WP_281957854.1 464320..465567(-) (htrA) [Enterococcus cecorum isolate CIRMBP-1281]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTGATTGGTGGTGCTCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGAAA
CTAAAGTTAAAAATGTGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCAGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAGTCAAAATAGCGGTACTTTGGAAACAGCCAGTGAAGGTAGTGGTGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTAACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
AGATTCAGATAGTCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACTGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCCTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGTCAAGAAGTCAATATCAATGCCATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TGGTCAATATCATTAACCAACTAGAACAAAGTGGGAAAGTGACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACAAACATCTTAAAAGTACCTGCCTCATTAAATGAAGGTGTCGTGCTTGCTCAAGTCAA
TAGCGCAACGCCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTGAAAAGGTCAATGATG
GCACTGCATTAAGAGCCGCGCTTTATAAAAAACAAGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(120-265)

PDZ domain (PDZ_2)

(310-407)

Peptidase family M50 (Peptidase_M50)

(251-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.303

86.024

0.484
  htrA Streptococcus gordonii str. Challis substr. CH1

48.649

98.072

0.477
  htrA Streptococcus mitis NCTC 12261

50.131

91.807

0.46
  htrA Streptococcus pneumoniae TIGR4

53.295

84.096

0.448
  htrA Streptococcus pneumoniae D39

53.295

84.096

0.448
  htrA Streptococcus pneumoniae Rx1

53.295

84.096

0.448
  htrA Streptococcus pneumoniae R6

53.295

84.096

0.448

Multiple sequence alignment