Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QML50_RS02060 Genome accession   NZ_OX346403
Coordinates   393823..395070 (-) Length   415 a.a.
NCBI ID   WP_171333157.1    Uniprot ID   -
Organism   Enterococcus cecorum isolate CIRMBP-1283     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 388823..400070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML50_RS02025 (CIRMBP1283_00403) - 388973..389284 (+) 312 WP_016251466.1 thioredoxin family protein -
  QML50_RS02030 (CIRMBP1283_00404) - 389307..389750 (+) 444 WP_016251467.1 universal stress protein -
  QML50_RS02035 (CIRMBP1283_00405) - 389795..390397 (+) 603 WP_080961497.1 CadD family cadmium resistance transporter -
  QML50_RS02040 (CIRMBP1283_00406) ytpR 390476..391087 (+) 612 WP_047334171.1 YtpR family tRNA-binding protein -
  QML50_RS02045 (CIRMBP1283_00407) - 391155..391325 (-) 171 WP_168930749.1 hypothetical protein -
  QML50_RS02050 (CIRMBP1283_00408) - 391328..392557 (-) 1230 WP_047242911.1 MFS transporter -
  QML50_RS02055 (CIRMBP1283_00409) - 392926..393582 (+) 657 WP_047242864.1 Crp/Fnr family transcriptional regulator -
  QML50_RS02060 (CIRMBP1283_00410) htrA 393823..395070 (-) 1248 WP_171333157.1 trypsin-like peptidase domain-containing protein Regulator
  QML50_RS02065 (CIRMBP1283_00411) rlmH 395527..396006 (+) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QML50_RS02070 (CIRMBP1283_00412) - 396014..396712 (+) 699 WP_113785142.1 hydrolase -
  QML50_RS02075 (CIRMBP1283_00413) - 396860..398038 (+) 1179 WP_281956876.1 MalY/PatB family protein -
  QML50_RS02080 (CIRMBP1283_00414) - 398065..399165 (+) 1101 WP_281956660.1 PLP-dependent transferase -
  QML50_RS02085 (CIRMBP1283_00415) - 399168..399917 (+) 750 WP_281956661.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43084.06 Da        Isoelectric Point: 5.4559

>NTDB_id=1154980 QML50_RS02060 WP_171333157.1 393823..395070(-) (htrA) [Enterococcus cecorum isolate CIRMBP-1283]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHATSSTGIQSAQTATKVKNVKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGSLEDFFGAQQGNSSSQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDSLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPASLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGEKVNDGTALRAALYKKQVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=1154980 QML50_RS02060 WP_171333157.1 393823..395070(-) (htrA) [Enterococcus cecorum isolate CIRMBP-1283]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTGATTGGTGGTGCTCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATGCGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTAAAAATGTGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCAGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAGTCAAAATAGCGGTACTTTGGAAACAGCCAGTGAAGGTAGTGGTGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTAACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
AGATTCAGATAGTCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACTGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCCTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGTCAAGAAGTCAATATCAATGCCATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATTGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TGGTCAACATTATTAATCAACTAGAACAAAGTGGGAAAGTAACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACAAACATCTTAAAAGTACCTGCCTCATTAAATGAAGGTGTCGTGCTTGCTCAAGTCAA
TAGCGCAACGCCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTGAAAAGGTCAATGATG
GCACTGCATTAAGAGCCGCGCTTTATAAAAAACAAGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(120-265)

PDZ domain (PDZ_2)

(310-407)

Peptidase family M50 (Peptidase_M50)

(251-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.461

85.783

0.484
  htrA Streptococcus gordonii str. Challis substr. CH1

49.14

98.072

0.482
  htrA Streptococcus pneumoniae R6

48.529

98.313

0.477
  htrA Streptococcus pneumoniae TIGR4

48.529

98.313

0.477
  htrA Streptococcus pneumoniae D39

48.529

98.313

0.477
  htrA Streptococcus pneumoniae Rx1

48.529

98.313

0.477
  htrA Streptococcus mitis NCTC 12261

50.131

91.807

0.46

Multiple sequence alignment