Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QML79_RS10505 Genome accession   NZ_OX346402
Coordinates   2117627..2118874 (+) Length   415 a.a.
NCBI ID   WP_016251474.1    Uniprot ID   -
Organism   Enterococcus cecorum isolate CIRMBP-1261     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2112627..2123874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML79_RS10480 - 2112781..2113529 (-) 749 Protein_2020 NADPH-dependent oxidoreductase -
  QML79_RS10485 (CIRMBP1261_02102) - 2113532..2114632 (-) 1101 WP_047341549.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  QML79_RS10490 (CIRMBP1261_02103) - 2114659..2115837 (-) 1179 WP_047341550.1 MalY/PatB family protein -
  QML79_RS10495 (CIRMBP1261_02104) - 2115985..2116683 (-) 699 WP_047338837.1 hydrolase -
  QML79_RS10500 (CIRMBP1261_02105) rlmH 2116691..2117170 (-) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QML79_RS10505 (CIRMBP1261_02106) htrA 2117627..2118874 (+) 1248 WP_016251474.1 trypsin-like peptidase domain-containing protein Regulator
  QML79_RS10510 (CIRMBP1261_02107) - 2119115..2119771 (-) 657 WP_281956329.1 Crp/Fnr family transcriptional regulator -
  QML79_RS10515 (CIRMBP1261_02108) - 2120140..2121369 (+) 1230 WP_047242911.1 MFS transporter -
  QML79_RS10520 (CIRMBP1261_02109) - 2121372..2121542 (+) 171 WP_167541418.1 hypothetical protein -
  QML79_RS10525 (CIRMBP1261_02110) ytpR 2121750..2122361 (-) 612 WP_047341551.1 YtpR family tRNA-binding protein -
  QML79_RS10530 (CIRMBP1261_02111) - 2122440..2123042 (-) 603 WP_080961488.1 CadD family cadmium resistance transporter -
  QML79_RS10535 (CIRMBP1261_02112) - 2123087..2123530 (-) 444 WP_047341552.1 universal stress protein -
  QML79_RS10540 (CIRMBP1261_02113) - 2123553..2123864 (-) 312 WP_047341553.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43114.09 Da        Isoelectric Point: 5.4559

>NTDB_id=1154968 QML79_RS10505 WP_016251474.1 2117627..2118874(+) (htrA) [Enterococcus cecorum isolate CIRMBP-1261]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTATKVKNVKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGSLEDFFGAQQGNSSSQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDSLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPASLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGEKVNDGTALRAALYKKQVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=1154968 QML79_RS10505 WP_016251474.1 2117627..2118874(+) (htrA) [Enterococcus cecorum isolate CIRMBP-1261]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTAATTGGTGGTGCCCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTAAAAATGTGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCAGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAGTCAAAATAGCGGTACTTTGGAAACAGCCAGTGAAGGTAGTGGTGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTAACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGTTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
AGATTCAGATAGTCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACTGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCCTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGTCAAGAAGTCAATATCAATGCTATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TCGTCAATATTATTAATCAACTAGAACAAAGTGGGAAAGTAACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACAAACATCTTAAAAGTACCTGCCTCATTAAATGAAGGTGTCGTGCTTGCTCAAGTCAA
TAGCGCAACGCCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTGAAAAGGTCAATGATG
GCACTGCATTAAGAGCCGCGCTTTATAAAAAACAAGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(310-407)

Peptidase family M50 (Peptidase_M50)

(251-410)

Trypsin-like peptidase domain (Trypsin_2)

(120-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.461

85.783

0.484
  htrA Streptococcus gordonii str. Challis substr. CH1

48.649

98.072

0.477
  htrA Streptococcus pneumoniae R6

48.529

98.313

0.477
  htrA Streptococcus pneumoniae TIGR4

48.529

98.313

0.477
  htrA Streptococcus pneumoniae D39

48.529

98.313

0.477
  htrA Streptococcus pneumoniae Rx1

48.529

98.313

0.477
  htrA Streptococcus mitis NCTC 12261

50.131

91.807

0.46

Multiple sequence alignment