Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   NBW44_RS05335 Genome accession   NZ_OW724079
Coordinates   1066365..1068215 (-) Length   616 a.a.
NCBI ID   WP_250307514.1    Uniprot ID   -
Organism   Streptococcus sp. Marseille-Q3533     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1061365..1073215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBW44_RS05310 - 1061417..1062382 (+) 966 WP_250307512.1 LacI family DNA-binding transcriptional regulator -
  NBW44_RS05315 - 1062422..1063696 (-) 1275 WP_250307985.1 hydroxymethylglutaryl-CoA reductase, degradative -
  NBW44_RS05320 - 1063696..1064868 (-) 1173 WP_250307513.1 hydroxymethylglutaryl-CoA synthase -
  NBW44_RS05325 - 1065046..1065495 (-) 450 WP_075567996.1 threonine/serine exporter family protein -
  NBW44_RS05330 - 1065497..1066258 (-) 762 WP_075567997.1 threonine/serine exporter family protein -
  NBW44_RS05335 stkP 1066365..1068215 (-) 1851 WP_250307514.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NBW44_RS05340 - 1068212..1068952 (-) 741 WP_075567999.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NBW44_RS05345 rsmB 1068968..1070281 (-) 1314 WP_250307515.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NBW44_RS05350 fmt 1070274..1071209 (-) 936 WP_250307516.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 616 a.a.        Molecular weight: 68254.30 Da        Isoelectric Point: 7.3648

>NTDB_id=1152605 NBW44_RS05335 WP_250307514.1 1066365..1068215(-) (stkP) [Streptococcus sp. Marseille-Q3533]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHAKGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFFEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QSLENVVIKATAKKLTDRYQTVSEMYVDLLSSLSYNRRNEPKLVFEDTSKVDTKTLPKISQSTLTAIPKVQPKEESPQTK
KPSVQAAPKPKEVAKPVKKRRFKARYLVLLASFILVLSSILWIISKTPATVVIPKVAGQTVAEAKETLKNANFEIGEEKD
ESSDTVEEGRVIRTDPESGTNRKEGTKINLIVSSGKPSFPIGNYIGRKSSDVVAELKDKKVPENLIKIVEEESSETEPGL
VMRQSLSEGTIYDLSKATEITLTVAKKVTTVSMPYYIGSSLEFTKNNLIQVVGVKEANIEVVEVSTVLEGTIEGTVINQS
PKPYEDLDLSKTHVKISVYKPKPMTTTQVPHENRIEVTPPQTREAETSQTTTHEHN

Nucleotide


Download         Length: 1851 bp        

>NTDB_id=1152605 NBW44_RS05335 WP_250307514.1 1066365..1068215(-) (stkP) [Streptococcus sp. Marseille-Q3533]
ATGATCCAGATCGGCAAGATTTTTGCCGGACGGTATCGAATTATCAAACAAATTGGTCGTGGAGGCATGGCAGATGTATA
CCTGGCCAAGGATTTGATTTTAGATGGGGAAGAGGTAGCTGTAAAGGTCCTGAGGACCAACTACCAGACGGATCCTATAG
CTGTTGCGCGTTTTCAACGGGAAGCGCGAGCGATGGCAGACTTGGATCATCCTCATATCGTTCGGATTACTGATATTGGT
GAAGAAGATGGTCAGCAATACCTAGCTATGGAATACGTAGCCGGTCTCGATCTTAAGCGATATATTAAAGAACACTATCC
TCTTTCAAATGAGGAAGCAGTTCGTATCATGGGTCAGATCTTGCTAGCTATGCGTTTAGCACATGCAAAAGGAATTGTTC
ACCGTGATTTAAAGCCTCAAAATATTCTCTTGACTCCAGATGGAACAGCTAAGGTTACTGACTTTGGTATCGCGGTAGCT
TTTGCGGAAACCAGCTTGACTCAAACTAACTCTATGTTGGGCTCTGTCCACTATTTATCGCCTGAACAGGCTCGTGGCTC
TAAAGCTACGTTTCAGAGTGATATTTATGCCATGGGAATTATTTTCTTTGAAATGTTAACAGGGCATATCCCATATGATG
GAGATAGTGCGGTCACGATTGCCCTTCAGCATTTTCAGAAACCACTCCCATCTGTTATAGCTGAAAATCCTTCAGTACCA
CAATCATTAGAAAACGTTGTTATTAAAGCGACAGCTAAAAAGTTGACAGACCGTTATCAAACTGTCTCAGAGATGTATGT
TGACTTATTGAGCAGTCTTTCTTATAACCGTCGAAATGAACCAAAACTGGTATTTGAAGATACAAGTAAAGTTGATACAA
AAACCTTACCGAAAATTTCACAATCTACTTTAACAGCGATTCCTAAAGTGCAACCAAAGGAAGAAAGTCCTCAGACTAAG
AAACCGAGTGTTCAAGCAGCTCCTAAACCTAAGGAAGTAGCTAAGCCGGTGAAGAAGCGTCGCTTTAAGGCTCGTTACTT
GGTTCTCCTTGCTAGTTTTATTCTGGTGCTCTCTTCTATACTATGGATTATATCTAAGACGCCAGCAACTGTTGTGATTC
CGAAAGTAGCAGGGCAAACAGTGGCTGAGGCTAAAGAAACTCTTAAAAATGCCAATTTTGAAATTGGTGAAGAGAAAGAT
GAATCCAGTGATACAGTAGAAGAAGGCCGAGTTATTCGAACGGACCCAGAATCAGGAACCAATCGTAAAGAAGGAACTAA
GATTAATCTGATTGTTTCATCAGGTAAACCTTCATTCCCGATAGGGAACTATATCGGACGAAAATCTTCAGATGTAGTAG
CAGAGTTAAAAGACAAGAAAGTCCCAGAAAATCTGATTAAGATTGTTGAGGAAGAATCGAGTGAAACTGAACCTGGTCTT
GTCATGAGACAAAGTTTGTCAGAAGGAACAATTTACGATCTTAGCAAGGCGACTGAGATTACCTTGACAGTTGCTAAAAA
GGTTACAACTGTTTCAATGCCTTATTATATCGGCTCAAGTCTTGAATTTACAAAGAATAATTTGATTCAAGTTGTGGGTG
TTAAAGAAGCTAATATTGAGGTAGTAGAAGTTTCTACAGTTCTTGAGGGAACTATTGAAGGTACTGTAATCAATCAGAGT
CCAAAACCATACGAGGATCTTGATCTTAGCAAAACTCATGTTAAAATCTCTGTTTATAAACCAAAACCAATGACTACAAC
ACAAGTACCCCATGAGAATAGAATCGAGGTAACACCTCCTCAAACTCGTGAGGCAGAAACTAGTCAAACAACAACACATG
AGCATAACTGA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(443-506)

PASTA domain (PASTA)

(371-433)

Protein kinase domain (Pkinase)

(12-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.108

94.318

0.727
  stkP Streptococcus pneumoniae D39

76.764

94.318

0.724
  stkP Streptococcus pneumoniae R6

76.764

94.318

0.724
  stkP Streptococcus pneumoniae Rx1

76.592

94.318

0.722
  pknB Streptococcus mutans UA159

56.102

89.123

0.5
  stkP/pknB Streptococcus salivarius strain HSISS4

59.592

79.545

0.474

Multiple sequence alignment