Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NBW44_RS01605 Genome accession   NZ_OW724079
Coordinates   298430..299185 (+) Length   251 a.a.
NCBI ID   WP_250307972.1    Uniprot ID   -
Organism   Streptococcus sp. Marseille-Q3533     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 293430..304185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBW44_RS01590 - 294035..294838 (+) 804 WP_250306934.1 LicD family protein -
  NBW44_RS01595 - 294839..295645 (+) 807 WP_250306935.1 phosphorylcholine transferase LicD -
  NBW44_RS01600 - 295714..298275 (+) 2562 WP_250306936.1 MBL fold metallo-hydrolase -
  NBW44_RS01605 mecA 298430..299185 (+) 756 WP_250307972.1 adaptor protein MecA Regulator
  NBW44_RS01610 - 299410..299973 (+) 564 WP_250306937.1 TIGR01440 family protein -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29309.94 Da        Isoelectric Point: 3.9496

>NTDB_id=1152585 NBW44_RS01605 WP_250307972.1 298430..299185(+) (mecA) [Streptococcus sp. Marseille-Q3533]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELSKMSPDEFLKTLEKTLAEKTKDDIEAIQSLEQVEKEEEEESEEDVEEVSDIHEESTKEPYIY
YILQFDNLTSLVSFSKTVNFEMETSELYKMNNQYYLTILVDIENHPKPYPAWLLARMREYADDSDLSRSVLQEYGQVLIN
HDAVQGLQKVQ

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1152585 NBW44_RS01605 WP_250307972.1 298430..299185(+) (mecA) [Streptococcus sp. Marseille-Q3533]
ATGAAAATGAAACAAATCAGTGATACCACACTAAAAATCACCATGTCTTTAGAAGATTTGATGGACAGGGGAATGGAAAT
TGCGGATTTTCTTGTTCCACAAGAAAAAACGGAAGAATTCTTTTATGCTATCTTGGATGAGTTAGAGATGCCAGACAGTT
TCTTGGATACAGGGATGCTTAGTTTTCGAGTGACTCCTAAGCCTGACAAAGTGGATGTCTTTGTGACCAAGTCTAAGATT
GACCAAAATTTGGATTTTGAGGATTTGGCAGATCTTCCGGATATGGAAGAATTATCAAAAATGTCTCCAGATGAGTTTTT
GAAAACTTTGGAAAAAACTTTAGCAGAGAAAACAAAAGATGATATTGAAGCTATTCAGTCTTTGGAACAGGTTGAAAAAG
AAGAAGAGGAAGAAAGCGAAGAAGATGTAGAGGAAGTTTCGGATATCCATGAAGAGTCTACTAAAGAACCCTACATCTAC
TATATCCTTCAATTTGACAATTTAACTAGCTTAGTCTCTTTCTCAAAGACAGTAAATTTTGAGATGGAAACATCGGAACT
CTATAAGATGAATAATCAGTATTACTTAACGATCTTAGTAGATATTGAAAATCATCCTAAACCATACCCTGCCTGGCTAT
TAGCCCGAATGAGAGAGTATGCTGATGACAGTGATTTAAGTCGTTCAGTTTTGCAGGAGTATGGCCAAGTCTTAATTAAC
CATGATGCCGTGCAAGGGCTACAAAAGGTACAATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

82.8

99.602

0.825
  mecA Streptococcus pneumoniae D39

82.8

99.602

0.825
  mecA Streptococcus pneumoniae R6

82.8

99.602

0.825
  mecA Streptococcus pneumoniae TIGR4

82.8

99.602

0.825
  mecA Streptococcus mutans UA159

48.4

99.602

0.482
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.474
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.47

Multiple sequence alignment